Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229633 | 1.00 | ALDH1A1 (0.52) | ALDH1A1GAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL11102060 | 0.83 | RAB9A (0.53) | ALDH1A1GAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL11102063 | 0.83 | RAB9A (0.53) | ALDH1A1GAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL11218903 | 0.82 | CES2 (0.53) | ALDH1A1GAASMN1; SMN2RAB9AMAPT | |
| SCHEMBL6833469 | 0.82 | CES2 (0.53) | ALDH1A1GAASMN1; SMN2RAB9AMAPT | |
| SCHEMBL6833468 | 0.82 | CES2 (0.53) | ALDH1A1GAASMN1; SMN2RAB9AMAPT | |
| SCHEMBL11221822 | 0.81 | ALDH1A1 (0.51) | ALDH1A1GAALMNAMAPTHTT | |
| SCHEMBL11221841 | 0.81 | ALDH1A1 (0.51) | ALDH1A1GAALMNAMAPTHTT | |
| SCHEMBL1070286 | 0.80 | MEN1 (0.53) | ALDH1A1GAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL31523812 | 0.80 | MAPT (0.48) | ALDH1A1GAASMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342781-A | PREVENTING AND TREATING ALLERGIC BRONCHIAL ASTHMA, RHINITIS AND SKIN DISORDERS | PFIZER INC. (US) | 1982-08-03 | — | — | US | disclosed |