SCHEMBL1122199

SCHEMBL1122199

CCCCCCCC(=O)Oc1[nH]c2cccc(Cl)c2c1Br

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLM Q9NP87 2/20 0.40
POLK Q9UBT6 2/20 0.40
POLL Q9UGP5 2/20 0.40
POLH Q9Y253 2/20 0.40
HTR2A P28223 2/20 0.39
HPGD P15428 1/20 0.37
GPR17 Q13304 1/20 0.37
NR4A2 P43354 1/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
EPHX2 P34913 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
SERPINE1 P05121 1/20 0.35
SPHK2 Q9NRA0 1/20 0.35
SPHK1 Q9NYA1 1/20 0.35
TOP2A P11388 1/20 0.35
MCL1 Q07820 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122190 0.88 POLM (0.41) POLMPOLKPOLLPOLHHTR2A
SCHEMBL5009804 0.84 POLM (0.40) POLMPOLKPOLLPOLHHTR2A
SCHEMBL1122036 0.81 GAA (0.46) HPGDALDH1A1MAPK1
SCHEMBL1122593 0.78 HPGD (0.40) POLMPOLKPOLLPOLHHTR2A
SCHEMBL1121911 0.76 GAA (0.46) HPGDKMT2ASMN1; SMN2ALDH1A1MAPK1
SCHEMBL1121861 0.72 GAA (0.47) HPGDKMT2ASMN1; SMN2MEN1ALDH1A1
SCHEMBL1122600 0.71 MGAM (0.46) HPGDSMN1; SMN2ALDH1A1MAPK1
SCHEMBL1122592 0.71 POLM (0.40) POLMPOLKPOLLPOLHHTR2A
SCHEMBL9322247 0.70 KMT2A (0.57) POLMPOLKPOLLPOLHKMT2A
SCHEMBL8088316 0.70 KMT2A (0.57) POLMPOLKPOLLPOLHKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP claimed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP claimed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US claimed
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US disclosed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP disclosed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP disclosed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US disclosed