SCHEMBL1122592

SCHEMBL1122592

CCCCCCCC(=O)Oc1c(Cl)c2c(Cl)cccc2n1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLM Q9NP87 2/20 0.40
POLK Q9UBT6 2/20 0.40
POLL Q9UGP5 2/20 0.40
POLH Q9Y253 2/20 0.40
KMT2A Q03164 5/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CNR2 P34972 3/20 0.38
MEN1 O00255 3/20 0.38
CNR1 P21554 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
EPHX2 P34913 2/20 0.36
HPGD P15428 1/20 0.36
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
ATM Q13315 1/20 0.35
HTR2A P28223 1/20 0.35
KDM4E B2RXH2 1/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122189 0.83 L3MBTL1 (0.43) POLMPOLKPOLLPOLHKMT2A
SCHEMBL1122190 0.75 POLM (0.41) POLMPOLKPOLLPOLHKMT2A
SCHEMBL1122197 0.75 HTR7 (0.39) POLMPOLKPOLLPOLHKMT2A
SCHEMBL8675342 0.72 POLM (0.54) POLMPOLKPOLLPOLHKMT2A
SCHEMBL27508353 0.71 KMT2A (0.57) POLMPOLKPOLLPOLHKMT2A
SCHEMBL8088316 0.71 KMT2A (0.57) POLMPOLKPOLLPOLHKMT2A
SCHEMBL9322247 0.71 KMT2A (0.57) POLMPOLKPOLLPOLHKMT2A
SCHEMBL5009804 0.71 POLM (0.40) POLMPOLKPOLLPOLHKMT2A
SCHEMBL1122199 0.71 POLM (0.40) POLMPOLKPOLLPOLHKMT2A
SCHEMBL15548023 0.70 POLM (0.55) POLMPOLKPOLLPOLHKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US claimed
JP-4794627-B2 2011-10-19 JP claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP claimed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP claimed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US claimed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP claimed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO claimed
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US disclosed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US disclosed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP disclosed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO disclosed