SCHEMBL1122190

SCHEMBL1122190

CCCCCCCC(=O)Oc1[nH]c2cccc(Cl)c2c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLM Q9NP87 2/20 0.41
POLK Q9UBT6 2/20 0.41
POLL Q9UGP5 2/20 0.41
POLH Q9Y253 2/20 0.41
HTR2A P28223 2/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPGD P15428 1/20 0.39
GPR17 Q13304 1/20 0.38
MCL1 Q07820 1/20 0.38
NR4A2 P43354 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
EPHX2 P34913 1/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
SERPINE1 P05121 1/20 0.36
SPHK2 Q9NRA0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122199 0.88 POLM (0.40) POLMPOLKPOLLPOLHHTR2A
SCHEMBL1122593 0.88 HPGD (0.40) POLMPOLKPOLLPOLHHTR2A
SCHEMBL1121911 0.82 GAA (0.46) KMT2AALDH1A1MAPK1HPGDSMN1; SMN2
SCHEMBL5009804 0.81 POLM (0.40) POLMPOLKPOLLPOLHHTR2A
SCHEMBL1122592 0.75 POLM (0.40) POLMPOLKPOLLPOLHHTR2A
SCHEMBL1121861 0.73 GAA (0.47) KMT2AMEN1ALDH1A1MAPK1HPGD
SCHEMBL8675342 0.73 POLM (0.54) POLMPOLKPOLLPOLHHTR2A
SCHEMBL1122036 0.72 GAA (0.46) ALDH1A1MAPK1HPGDKDM4ELMNA
SCHEMBL1122600 0.72 MGAM (0.46) ALDH1A1MAPK1HPGDSMN1; SMN2KDM4E
SCHEMBL9322247 0.72 KMT2A (0.57) POLMPOLKPOLLPOLHKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US claimed
JP-4794627-B2 2011-10-19 JP claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP claimed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP claimed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US claimed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP claimed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO claimed
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US disclosed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP disclosed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP disclosed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US disclosed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP disclosed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO disclosed