Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.55 |
| ▸ | PLD1 | Q13393 | 7/20 | 0.54 |
| ▸ | PLD2 | O14939 | 6/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206461 | 0.91 | HSD11B1 (0.64) | HSD11B1OPRM1PLD1PLD2HTR1A | |
| SCHEMBL11032636 | 0.88 | PLD1 (0.64) | HSD11B1OPRM1PLD1PLD2 | |
| SCHEMBL11258172 | 0.84 | OPRM1 (0.58) | HSD11B1OPRM1PLD1PLD2HTR1A | |
| SCHEMBL11033800 | 0.79 | HSD11B1 (0.62) | HSD11B1OPRM1PLD1PLD2 | |
| SCHEMBL7709273 | 0.78 | OPRM1 (0.72) | OPRM1PLD1PLD2HTR1AADRA2A | |
| SCHEMBL11205387 | 0.78 | PLD1 (0.56) | HSD11B1OPRM1PLD1PLD2DRD2 | |
| SCHEMBL11251753 | 0.77 | OPRM1 (0.60) | HSD11B1OPRM1PLD1PLD2HTR1A | |
| SCHEMBL10712205 | 0.76 | PLD1 (0.53) | HSD11B1OPRM1PLD1PLD2HTR1A | |
| SCHEMBL25802931 | 0.76 | OPRM1 (0.70) | OPRM1PLD1PLD2HTR1AADRA2A | |
| SCHEMBL11199327 | 0.76 | PLD1 (0.51) | HSD11B1OPRM1PLD1PLD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092391-A2 | Novel piperidine derivatives and pharmaceutical compositions containing same | KYOWA HAKKO KOGYO CO., LTD (JP) | 1983-10-26 | — | — | EP | disclosed |