Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30775137 | 0.74 | ACHE (0.43) | SLC7A5ACHEBLMPTGS1LMNA | |
| SCHEMBL350703 | 0.72 | SLC7A5 (0.53) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL350704 | 0.72 | SLC7A5 (0.53) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL5323193 | 0.70 | SLC7A5 (0.40) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL5323185 | 0.70 | SLC7A5 (0.40) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL3930054 | 0.69 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| Bicarbonate SCHEMBL12986986 | 0.69 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL29524472 | 0.69 | SLC7A5 (0.57) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL5284864 | 0.69 | SLC7A5 (0.57) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL8626747 | 0.69 | SLC7A5 (0.65) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016611-B1 | TRIPEPTIDES, PROCESS FOR THEIR PREPARATION, THERAPEUTIC COMPOSITIONS CONTAINING THEM AND METHODS FOR THEIR USE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-08-17 | — | — | EP | disclosed |
| EP-0016611-A2 | Tripeptides, process for their preparation, therapeutic compositions containing them and methods for their use | ORTHO PHARMACEUTICAL CORPORATION (US) | 1980-10-01 | — | — | EP | disclosed |
| US-4215112-A | IMMUNOLOGY; GLANDULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1980-07-29 | — | — | US | disclosed |