Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.52 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233277 | 0.85 | ALDH1A1 (0.39) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9892782 | 0.85 | RAB9A (0.54) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL11227159 | 0.81 | SMN1; SMN2 (0.50) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL11456066 | 0.79 | SMN1; SMN2 (0.35) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL11246825 | 0.78 | SMN1; SMN2 (0.33) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11222233 | 0.78 | SMN1; SMN2 (0.38) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL1855039 | 0.76 | RAB9A (0.58) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL11230077 | 0.75 | NPC1 (0.36) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11447780 | 0.73 | NPC1 (0.31) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11236660 | 0.72 | ADORA3 (0.60) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337081-A | 5-Amido-3-trihalomethyl-1,2,4-thiadiazoles and their use as herbicides | OLIN CORPORATION (US) | 1982-06-29 | — | — | US | disclosed |