Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN2 | Q9H2S1 | 4/20 | 0.38 |
| ▸ | KCNN3 | Q9UGI6 | 4/20 | 0.38 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | SLC18A2 | Q05940 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11225508 | 0.93 | KCNN2 (0.39) | KCNN2KCNN3KCNN1KDM4EALDH1A1 | |
| SCHEMBL11221051 | 0.81 | SLC18A2 (0.39) | KCNN2KCNN3KCNN1KDM4EALDH1A1 | |
| SCHEMBL11226035 | 0.80 | KLK7 (0.40) | KCNN2KCNN3KCNN1ABCB1KDM4E | |
| SCHEMBL11223896 | 0.77 | KLK7 (0.37) | KCNN2KCNN3KCNN1ABCB1KDM4E | |
| SCHEMBL11370360 | 0.76 | MAOA (0.41) | KCNN2KCNN3KCNN1SLC18A2MAOA | |
| SCHEMBL11220353 | 0.76 | MAOA (0.41) | KCNN2KCNN3KCNN1SLC18A2MAOA | |
| SCHEMBL11222498 | 0.76 | KCNN2 (0.42) | KCNN2KCNN3KCNN1ABCB1KDM4E | |
| SCHEMBL11226482 | 0.75 | KCNN2 (0.41) | KCNN2KCNN3KCNN1ABCB1MAOA | |
| SCHEMBL11227592 | 0.74 | KCNN2 (0.36) | KCNN2KCNN3KCNN1ALDH1A1KLK7 | |
| SCHEMBL11225822 | 0.73 | SLC18A2 (0.40) | KCNN2KCNN3KCNN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352805-A | BENZOXEPINE DERIVATIVES | THE UPJOHN COMPANY (US) | 1982-10-05 | — | — | US | disclosed |
| US-4312868-A | HYPOTENSIVE, ANTIPSYCHOTIC | THE UPJOHN COMPANY (US) | 1982-01-26 | — | — | US | disclosed |
| US-4251526-A | HYPOTENSIVE AGENTS AND ANTIPSYCHOTIC | PHARMACIA & UPJOHN COMPANY | 1981-02-17 | — | — | US | disclosed |
| US-4250181-A | HYPOTENSIVE AGENTS, ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1981-02-10 | — | — | US | disclosed |
| US-4250175-A | HYPOTENSIVE AGENTS, ANTIDEPRESSANTS | PHARMACIA & UPJOHN COMPANY | 1981-02-10 | — | — | US | disclosed |
| US-4247553-A | HYPOTENSIVE AGENTS, ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1981-01-27 | — | — | US | disclosed |
| US-4179510-A | ISOCHROMANS AND 2-BENZOXEPINS | THE UPJOHN COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4153612-A | 2-Benzoxepins | THE UPJOHN COMPANY (US) | 1979-05-08 | — | — | US | disclosed |