Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 5/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232288 | 0.77 | TDP1 (0.49) | MAPTMEN1KMT2A | |
| SCHEMBL11115835 | 0.76 | CCR1 (0.35) | HSD17B10MAPTMEN1PKMHTT | |
| SCHEMBL11118699 | 0.75 | MAPT (0.44) | HSD17B10MAPTKDM4EMEN1HTT | |
| SCHEMBL11229172 | 0.73 | LTA4H (0.38) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL11225305 | 0.73 | KDM4E (0.39) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL6323843 | 0.72 | APP (0.46) | HSD17B10MAPTKDM4EESR1MEN1 | |
| SCHEMBL11112106 | 0.72 | CCR1 (0.46) | MEN1KMT2ACCR1 | |
| SCHEMBL13174008 | 0.71 | HSD17B10 (0.54) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL28979837 | 0.70 | HSD17B10 (0.52) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL11478283 | 0.69 | ABL1 (0.51) | HSD17B10MAPTKDM4EESR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341403-A | Fluoran compounds, process for preparation thereof, and recording sheets using same | FUJI PHOTO FILM CO., LTD. (JP) | 1982-07-27 | — | — | US | disclosed |