Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 7/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13174008 | 0.79 | HSD17B10 (0.54) | HSD17B10TTRCYP3A4HPGDCRHBP | |
| SCHEMBL20375319 | 0.74 | ADRA2A (0.44) | HSD17B10CA1CA2CA9CAMK2A | |
| SCHEMBL3717777 | 0.72 | PDK1 (0.55) | HSD17B10TTRCYP3A4PDK1PDK2 | |
| SCHEMBL7003540 | 0.71 | ALDH1A1 (0.65) | HSD17B10TTRCYP3A4HPGDTNIK | |
| SCHEMBL3323425 | 0.71 | CA1 (0.58) | HSD17B10CYP3A4HPGDPDK1PDK2 | |
| SCHEMBL29264920 | 0.71 | S1PR1 (0.48) | HSD17B10TTRPDK1PDK2PDK3 | |
| Hydrochloric Acid SCHEMBL2541874 | 0.70 | PDK1 (0.45) | HSD17B10TTRPDK1PDK2PDK3 | |
| SCHEMBL11222456 | 0.70 | HSD17B10 (0.43) | HSD17B10TTRPDK1PDK2PDK3 | |
| SCHEMBL11546782 | 0.70 | HSD17B10 (0.43) | HSD17B10TTRPDK1PDK2PDK3 | |
| SCHEMBL224868 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115872906-A | Levatinib impurity and preparation method thereof | 山东铂源药业股份有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-115872906-A | Levatinib impurity and preparation method thereof | 山东铂源药业股份有限公司 | 2023-03-31 | — | — | CN | disclosed |