Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CISD1 | Q9NZ45 | 7/20 | 0.32 |
| ▸ | FERMT2 | Q96AC1 | 2/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116502 | 0.81 | ALDH1A1 (0.41) | TDP1CISD1HTTHSD17B10MAPT | |
| SCHEMBL11112106 | 0.78 | CCR1 (0.46) | CCR1TDP1FERMT2NR4A2MCL1 | |
| SCHEMBL11222456 | 0.76 | HSD17B10 (0.43) | CCR1HTTHSD17B10MEN1MAPT | |
| SCHEMBL10890242 | 0.76 | FERMT2 (0.41) | FERMT2HSD17B10CYP1A2 | |
| SCHEMBL11202348 | 0.75 | LMNA (0.46) | SMN1; SMN2MAPTPKM | |
| SCHEMBL11108942 | 0.75 | ALDH1A1 (0.61) | TDP1HTTSMN1; SMN2MEN1MAPT | |
| SCHEMBL11118699 | 0.72 | MAPT (0.44) | HTR1AADRA1DADRA1AADRA1BHTT | |
| SCHEMBL11232288 | 0.72 | TDP1 (0.49) | TDP1FERMT2HTR1AADRA1DADRA1A | |
| SCHEMBL11113719 | 0.71 | MEN1 (0.49) | HTTSMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL8293205 | 0.70 | PGK1 (0.39) | HTTSMN1; SMN2HSD17B10MCL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058868-B1 | DERIVATIVES OF TETRAHYDROPYRIMIDINON, PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THOSE DERIVATIVES AS ACTIVE PRODUCTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |
| US-4402731-A | Herbicidally active novel substituted tetrahydropyrimidinones | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-09-06 | — | — | US | disclosed |
| EP-0058868-A1 | Derivatives of tetrahydropyrimidinon, process for their preparation and herbicides containing those derivatives as active products | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1982-09-01 | — | — | EP | disclosed |