Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.35 |
| ▸ | HTR2C | P28335 | 9/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | IL1RN | P18510 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.30 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.30 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.30 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227830 | 0.68 | HSD11B1 (0.34) | IL1RNERAP2ERAP1 | |
| SCHEMBL11224580 | 0.66 | TDP1 (0.33) | IL1RNERAP2ERAP1 | |
| SCHEMBL11227905 | 0.65 | CYP3A4 (0.39) | — | |
| SCHEMBL2014602 | 0.64 | KDM1A (0.39) | USP2HPGDKDM1AKCNH2KDM1B | |
| SCHEMBL31342136 | 0.64 | KDM1A (0.39) | USP2HPGDKDM1AKCNH2KDM1B | |
| SCHEMBL11229583 | 0.64 | HCRTR1 (0.39) | — | |
| SCHEMBL23674528 | 0.63 | CDC7 (0.36) | KDM1AKCNH2KDM1B | |
| SCHEMBL11891671 | 0.62 | EPAS1 (0.34) | HTR2AHTR2CHTR2BKDM1AKCNH2 | |
| SCHEMBL30223191 | 0.62 | HTR2A (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL15821759 | 0.62 | CA1 (0.35) | HTR2AHTR2CHTR2BUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007243-B1 | 2-ARYL-1,3-CYCLOHEXANEDIONE COMPOUNDS AND ALKALI METAL SALTS, AMMONIUM SALTS AND ENOL ESTERS THEREOF, COMPOSITION AND METHOD OF CONTROLLING ACARINA ECTOPARASITES ON WARMBLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4257858-A | REACTING A CYCLOHEXA-1,3-DIONE-2-DIAZIDE WITH AN ARYL COMPOUND | UNION CARBIDE CORPORATION (US) | 1981-03-24 | — | — | US | disclosed |
| US-4256657-A | CYCLIZATION, ACID CATALYST | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4256658-A | CYCLIZATION, BASIC CATALYST | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4256659-A | Method of preparing 2-aryl-1,3-cyclohexanedione compounds | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4209532-A | Biocidal 2-aryl-1,3-cyclohexane dione compounds and alkali metal and ammonium salts thereof | UNION CARBIDE CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| EP-0007243-A1 | 2-Aryl-1,3-cyclohexanedione compounds and alkali metal salts, ammonium salts and enol esters thereof, composition and method of controlling acarina ectoparasites on warmblooded animals | UNION CARBIDE CORPORATION (US) | 1980-01-23 | — | — | EP | disclosed |
| US-4175135-A | Method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animal an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound, and alkali metal salts, ammonium salts and enol esters thereof | UNION CARBIDE CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |