Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 7/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17376705 | 0.89 | HCRTR2 (0.43) | HCRTR1HCRTR2ACHEPOLL | |
| SCHEMBL11224539 | 0.81 | CRHBP (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL17382579 | 0.81 | TP53 (0.46) | HCRTR1HCRTR2CA1CA2ACHE | |
| SCHEMBL11227830 | 0.77 | HSD11B1 (0.34) | KDM4E | |
| SCHEMBL15001063 | 0.74 | CRHBP (0.45) | HCRTR1HCRTR2ACHEPOLL | |
| SCHEMBL28054774 | 0.73 | ABCB1 (0.51) | CA1CA2CA4ACHEKDM4E | |
| SCHEMBL15821759 | 0.70 | CA1 (0.35) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL16268503 | 0.70 | NPSR1 (0.39) | CA1CA2CA4CA6 | |
| SCHEMBL30292812 | 0.69 | CA12 (0.35) | CA1CA2CA4ACHEKDM4E | |
| SCHEMBL6667331 | 0.69 | CA12 (0.35) | CA1CA2CA4ACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007243-B1 | 2-ARYL-1,3-CYCLOHEXANEDIONE COMPOUNDS AND ALKALI METAL SALTS, AMMONIUM SALTS AND ENOL ESTERS THEREOF, COMPOSITION AND METHOD OF CONTROLLING ACARINA ECTOPARASITES ON WARMBLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4257858-A | REACTING A CYCLOHEXA-1,3-DIONE-2-DIAZIDE WITH AN ARYL COMPOUND | UNION CARBIDE CORPORATION (US) | 1981-03-24 | — | — | US | disclosed |
| US-4256658-A | CYCLIZATION, BASIC CATALYST | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4256657-A | CYCLIZATION, ACID CATALYST | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4256659-A | Method of preparing 2-aryl-1,3-cyclohexanedione compounds | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4209532-A | Biocidal 2-aryl-1,3-cyclohexane dione compounds and alkali metal and ammonium salts thereof | UNION CARBIDE CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| EP-0007243-A1 | 2-Aryl-1,3-cyclohexanedione compounds and alkali metal salts, ammonium salts and enol esters thereof, composition and method of controlling acarina ectoparasites on warmblooded animals | UNION CARBIDE CORPORATION (US) | 1980-01-23 | — | — | EP | disclosed |
| US-4175135-A | Method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animal an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound, and alkali metal salts, ammonium salts and enol esters thereof | UNION CARBIDE CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |