Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.76 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | FABP7 | O15540 | 1/20 | 0.48 |
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29963136 | 1.00 | HSD17B1 (0.76) | HSD17B1HSD17B2ALDH1A1CYP1A2PKM | |
| SCHEMBL10724129 | 0.87 | HSD17B1 (0.62) | HSD17B1HSD17B2ALDH1A1CYP1A2PKM | |
| SCHEMBL15782656 | 0.84 | HSD17B1 (0.57) | HSD17B1HSD17B2ALDH1A1CYP1A2PYGL | |
| SCHEMBL28824840 | 0.84 | CASP6 (0.62) | HSD17B1HSD17B2ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL8752038 | 0.83 | NT5E (0.62) | HSD17B1HSD17B2CYP1A2HSD17B10CASP6 | |
| SCHEMBL1807568 | 0.83 | HSD17B1 (0.55) | HSD17B1HSD17B2ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL19355161 | 0.83 | HSD17B1 (0.55) | HSD17B1HSD17B2ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL11900180 | 0.83 | CASP6 (0.68) | HSD17B1HSD17B2ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL11594992 | 0.83 | HSD17B1 (0.55) | HSD17B1HSD17B2ALDH1A1CYP1A2PYGL | |
| SCHEMBL26885136 | 0.83 | HSD17B1 (0.55) | HSD17B1HSD17B2ALDH1A1PYGLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927153-A1 | METHOD FOR THE CARBOXYLATION ON AN AMINONAPHTOL | RHODIA CHIMIE (FR) | 1999-07-07 | — | — | EP | claimed |
| WO-1998011055-A1 | METHOD FOR THE CARBOXYLATION ON AN AMINONAPHTOL | RHODIA CHIMIE (FR) | 1998-03-19 | — | — | WO | claimed |
| US-20240352035-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-10-24 | — | — | US | disclosed |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| EP-3849496-B1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | UNIV OREGON HEALTH & SCIENCE (US) | 2023-10-25 | — | — | EP | disclosed |
| EP-3849496-B1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | UNIV OREGON HEALTH & SCIENCE (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-112804982-B | Near infrared nerve-retaining benzo [ c ] phenoxazine fluorophores | 俄勒冈健康与科学大学 | 2023-07-25 | — | — | CN | disclosed |
| US-20220041619-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-02-10 | — | — | US | disclosed |
| US-20220041619-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-02-10 | — | — | US | disclosed |
| CN-112804982-A | Benzo [ c ] phenoxazine fluorophores for near-infrared nerve retention | 俄勒冈健康与科学大学 | 2021-05-14 | — | — | CN | disclosed |
| US-20080015191-A1 | Pyrazines and Pyridines and Derivatives Thereof as Therapeutic Compounds | THE WELLCOME TRUST LIMITED (UK) | 2008-01-17 | — | — | US | disclosed |
| EP-1831184-A2 | PYRAZINES AND PYRIDINES AND DERIVATIVES THEREOF AS THERAPEUTIC COMPOUNDS | The Wellcome Trust Limited (GB) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006067466-A2 | PYRAZINES AND PYRIDINES AND DERIVATIVES THEREOF AS THERAPEUTIC COMPOUNDS | THE WELLCOME TRUST LIMITED (GB) | 2006-06-29 | — | — | WO | disclosed |
| EP-0927153-A1 | METHOD FOR THE CARBOXYLATION ON AN AMINONAPHTOL | RHODIA CHIMIE (FR) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011055-A1 | METHOD FOR THE CARBOXYLATION ON AN AMINONAPHTOL | RHODIA CHIMIE (FR) | 1998-03-19 | — | — | WO | disclosed |
| US-5677433-A | FOR TEXTILES, LEATHER, PAPER | ZENECA LIMITED (GB) | 1997-10-14 | — | — | US | disclosed |
| US-4703111-A | Water-soluble compounds containing one or two (nitrophenylamino)-phenylamino-chlorotriazinylamino groups, the nitrophenylamino being additionally substituted by a fiber-reactive group of the vinylsulfonyl series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT A CORP. OF GERMANY (DE) | 1987-10-27 | — | — | US | disclosed |
| US-4145340-A | WATER-SOLUBLE REACTIVE MONOAZO DYE CONTAINING A NONYLPHENOXY, CHLOROTRIAZINE GROUP | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-03-20 | — | — | US | disclosed |
| US-3966704-A | Naphthylazo naphthyl copper complex dyestuffs | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240352035-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | NTRK1, PMP22, PAX3 | HSD17B1 2979/4885HSD17B2 2589/4885ALDH1A1 1034/4885 |
| US-20080015191-A1 | Pyrazines and Pyridines and Derivatives Thereof as Therapeutic Compounds | BRAF, RAF1, BCOR | HSD17B1 1506/4885HSD17B2 1795/4885ALDH1A1 1620/4885 |
| US-12030893-B2 | Near-infrared nerve-sparing benzo[c]phenoxazine fluorophores | NTRK1, PMP22, PAX3 | HSD17B1 2979/4885HSD17B2 2589/4885ALDH1A1 1034/4885 |
| US-20220041619-A1 | NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES | NTRK1, PMP22, PAX3 | HSD17B1 2979/4885HSD17B2 2589/4885ALDH1A1 1034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.