Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | ALPL | P05186 | 2/20 | 0.60 |
| ▸ | ALPI | P09923 | 2/20 | 0.60 |
| ▸ | ALPG | P10696 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695093 | 0.85 | MAPT (0.82) | MAPTNPC1LMNACASP3SENP8 | |
| SCHEMBL1819229 | 0.84 | MAPT (0.58) | MAPTNPC1LMNACASP3SENP8 | |
| SCHEMBL23343879 | 0.78 | P2RX7 (0.50) | MAPTKMT2AHPGDGAARAB9A | |
| SCHEMBL7634744 | 0.77 | MAPT (0.57) | MAPTNPC1LMNACASP3SENP8 | |
| SCHEMBL13301158 | 0.77 | NPC1 (0.56) | MAPTNPC1LMNACASP3SENP8 | |
| SCHEMBL4345768 | 0.76 | HPGD (0.51) | MAPTLMNAKMT2AMEN1HPGD | |
| SCHEMBL2858346 | 0.75 | PKM (0.63) | NPC1LMNAALPLALPIALPG | |
| SCHEMBL12224103 | 0.75 | HPGD (0.62) | MAPTNPC1LMNACASP3SENP8 | |
| SCHEMBL10903296 | 0.75 | KMT2A (0.67) | NPC1LMNAALPLALPIALPG | |
| SCHEMBL10340461 | 0.75 | CYP1A2 (0.50) | MAPTKMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57058652-A | — | — | None | — | — | JP | disclosed |
| JP-S5758652-A | N-ALPHA,-ALPHA-DIMETHYLBENZYLACETAMIDE DERIVATIVE AND HERBICIDE | SHOWA DENKO KK | 1982-04-08 | — | — | JP | disclosed |