Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829561 | 0.86 | ALOX5 (0.50) | CYP1A2CYP3A4RECQLMAPK1F7 | |
| SCHEMBL30564476 | 0.81 | KIF11 (0.50) | CYP1A2CYP3A4RECQLMAPK1MAPT | |
| SCHEMBL23343879 | 0.81 | P2RX7 (0.50) | CYP1A2CYP3A4RECQLMAPK1F7 | |
| SCHEMBL27920436 | 0.80 | EPHX2 (0.55) | P2RX7KMT2AHDAC1HDAC3HDAC2 | |
| SCHEMBL4345768 | 0.80 | HPGD (0.51) | CYP1A2CYP3A4RECQLMAPK1F7 | |
| Hydrochloric Acid SCHEMBL29058723 | 0.79 | EPHX2 (0.54) | P2RX7KMT2AHDAC1HDAC3HDAC2 | |
| SCHEMBL9360320 | 0.79 | P2RX7 (0.55) | CYP1A2CYP3A4RECQLMAPK1P2RX7 | |
| Hydrochloric Acid SCHEMBL9172429 | 0.78 | MAPK1 (0.81) | CYP1A2CYP3A4RECQLMAPK1MAPT | |
| SCHEMBL10470727 | 0.78 | ESRRG (0.54) | MAPTKMT2AADAMTS4ADAMTS5HDAC1 | |
| SCHEMBL10890502 | 0.77 | KMT2A (0.53) | CYP1A2CYP3A4MAPK1F7P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904680-A | IMMUNOLOGY | SANKYO COMPANY, LIMITED (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0173441-B1 | AMINO ACID DERIVATIVES HAVING ANTI-TUMOR ACTIVITY AND COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1990-01-24 | — | — | EP | disclosed |
| EP-0173441-A1 | Amino acid derivatives having anti-tumor activity and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1986-03-05 | — | — | EP | disclosed |