Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15161819 | 0.82 | ALDH1A1 (0.35) | SMPD3DYRK1A | |
| SCHEMBL25317892 | 0.76 | GRM4 (0.38) | MAOAMAOB | |
| SCHEMBL20684696 | 0.69 | RPS6KA3 (0.46) | MAOAMAOB | |
| SCHEMBL31415171 | 0.69 | RPS6KA3 (0.46) | MAOAMAOB | |
| SCHEMBL11240403 | 0.67 | MAPT (0.46) | MAOAMAOB | |
| SCHEMBL3820785 | 0.67 | PRKCZ (0.45) | — | |
| SCHEMBL2397171 | 0.66 | MAPT (0.42) | — | |
| SCHEMBL751581 | 0.66 | HDAC8 (0.33) | — | |
| SCHEMBL3818490 | 0.66 | NPC1 (0.38) | — | |
| SCHEMBL973260 | 0.66 | CYP2A6 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341894-A | 2,4,6 TRI-SUBSTITUTED PYRYLIUM DYE SALTS | EASTMAN KODAK COMPANY (US) | 1982-07-27 | — | — | US | disclosed |
| US-4167412-A | COMPRISING A PYRYLIUM OR THIOPYRYLIUM SALT | EASTMAN KODAK COMPANY (US) | 1979-09-11 | — | — | US | disclosed |