Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 5/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5539865 | 0.79 | NISCH (0.37) | MAPTSMN1; SMN2SYKKDM4EALDH1A1 | |
| SCHEMBL1202054 | 0.77 | NOTUM (0.37) | SMN1; SMN2AURKAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL435455 | 0.76 | CYP1A2 (0.38) | MAPTSMN1; SMN2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL1980545 | 0.76 | ALDH1A1 (0.38) | MAPTSMN1; SMN2SYKKDM4EALDH1A1 | |
| SCHEMBL1973038 | 0.76 | MAPK14 (0.36) | MAPTALDH1A1NPC1RAB9ACCNB2 | |
| SCHEMBL8081622 | 0.75 | NISCH (0.38) | MAPTSMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL1967426 | 0.75 | CLK4 (0.56) | SMN1; SMN2SYKAURKAKDM4EALDH1A1 | |
| SCHEMBL10562349 | 0.75 | NPC1 (0.38) | MAPTSMN1; SMN2SYKALDH1A1TSHR | |
| SCHEMBL2397171 | 0.75 | MAPT (0.42) | MAPTSMN1; SMN2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL61346 | 0.72 | MAPT (0.56) | MAPTSMN1; SMN2SYKAURKAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341894-A | 2,4,6 TRI-SUBSTITUTED PYRYLIUM DYE SALTS | EASTMAN KODAK COMPANY (US) | 1982-07-27 | — | — | US | disclosed |
| US-4167412-A | COMPRISING A PYRYLIUM OR THIOPYRYLIUM SALT | EASTMAN KODAK COMPANY (US) | 1979-09-11 | — | — | US | disclosed |