Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230610 | 0.84 | ADRB2 (0.56) | KMT2AALDH1A1TSHRLMNAHPGD | |
| SCHEMBL5035248 | 0.83 | TSHR (0.53) | ALDH1A1TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL19316661 | 0.83 | ADRB2 (0.40) | SMN1; SMN2ALDH1A1TSHRADRB2ADRB1 | |
| SCHEMBL18382505 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTMAPK1USP2KMT2A | |
| SCHEMBL11662346 | 0.82 | TDP1 (0.51) | SMN1; SMN2MAPTMAPK1USP2KMT2A | |
| SCHEMBL5387921 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTMAPK1USP2KMT2A | |
| SCHEMBL13374673 | 0.81 | ADRB2 (0.60) | MAPTKMT2AALDH1A1TSHRHPGD | |
| SCHEMBL13135915 | 0.81 | ADRB2 (0.60) | SMN1; SMN2MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL11221791 | 0.80 | NPC1 (0.48) | MAPTKMT2AMEN1LMNAHTT | |
| SCHEMBL21603040 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TSHRADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4354008-A | CHELATING COMONOMER AND CHELATABLE TRANSITION METAL SALT | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1982-10-12 | — | — | US | claimed |
| US-4354008-A | CHELATING COMONOMER AND CHELATABLE TRANSITION METAL SALT | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1982-10-12 | — | — | US | disclosed |