Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237338 | 0.90 | SIGMAR1 (0.40) | HTR2ASIGMAR1TLR8LMNAHTT | |
| SCHEMBL8096435 | 0.87 | CALM1 (0.44) | HTR2ACALM1SIGMAR1LDHALDHB | |
| SCHEMBL11223954 | 0.86 | TP53 (0.41) | HTR2ACALM1MTNR1AMTNR1BTP53 | |
| SCHEMBL4250559 | 0.83 | CALM1 (0.44) | HTR2ACALM1IDH1ALOX5HPGD | |
| SCHEMBL301088 | 0.83 | ALDH1A1 (0.36) | ALOX5LTB4RLTB4R2KDM4EALDH1A1 | |
| SCHEMBL8093946 | 0.80 | HTR2A (0.46) | HTR2ACALM1LDHALDHBTP53 | |
| SCHEMBL8087736 | 0.77 | TLR8 (0.43) | HTR2ACALM1SIGMAR1TLR8LMNA | |
| SCHEMBL10598924 | 0.76 | HTR2A (0.48) | HTR2ACALM1LDHALDHBTP53 | |
| SCHEMBL28818542 | 0.76 | TSHR (0.47) | LDHALDHBLTB4RLTB4R2HTT | |
| SCHEMBL5249364 | 0.75 | HTR2A (0.63) | HTR2ACALM1LDHALDHBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339569-A | BULK POLYMERIZATION, BORON TRIFLUORIDE CATALYSTS | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1982-07-13 | — | — | US | disclosed |
| US-4087411-A | TRIOXANE, BORON FLUORIDE-TYPE CATALYST | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) | 1978-05-02 | — | — | US | disclosed |