Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024499 | 0.95 | ESR1 (0.49) | ESR1CYP19A1ESR2TYRGRM2 | |
| SCHEMBL9921244 | 0.87 | TAAR1 (0.46) | ESR1CYP19A1ESR2ALOX5ADRA1A | |
| SCHEMBL18641701 | 0.85 | ESR1 (0.46) | ESR1CYP19A1ESR2ALOX5MEN1 | |
| SCHEMBL28187525 | 0.84 | ALOX5 (0.67) | ESR1CYP19A1ESR2ALOX5MEN1 | |
| SCHEMBL28186787 | 0.83 | ALOX5 (0.70) | ESR1CYP19A1ESR2ALOX5MEN1 | |
| SCHEMBL28187534 | 0.83 | ALOX5 (0.70) | ESR1CYP19A1ESR2ALOX5MEN1 | |
| SCHEMBL28186760 | 0.83 | ALOX5 (0.70) | ESR1CYP19A1ESR2ALOX5MEN1 | |
| SCHEMBL28187615 | 0.83 | ALOX5 (0.70) | ESR1CYP19A1ESR2ALOX5MEN1 | |
| SCHEMBL19304105 | 0.82 | CHRM2 (0.54) | ESR1CYP19A1ESR2ADRA1ATAAR1 | |
| SCHEMBL22939735 | 0.82 | APLNR (0.56) | ALOX5MEN1KMT2ATSHRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366330-A | A FLUOROPHENOL CAPABLE OF BEING REACTED WITH AN ARYL OR CYCLOALKYL CARBOXYLIC ACID TO PRODUCT AN ESTER | BCH CHEMICALS LIMITED (GB) | 1982-12-28 | — | — | US | disclosed |