Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220069 | 0.82 | NAAA (0.55) | NAAAEGFREPHX1ALDH1A1HTT | |
| SCHEMBL11218890 | 0.82 | NAAA (0.55) | NAAAEGFREPHX1ALDH1A1HTT | |
| SCHEMBL11218806 | 0.82 | NAAA (0.55) | NAAAEGFREPHX1ALDH1A1HTT | |
| SCHEMBL11222408 | 0.82 | NAAA (0.55) | NAAAEGFREPHX1ALDH1A1HTT | |
| SCHEMBL11224412 | 0.82 | NAAA (0.55) | NAAAEGFREPHX1ALDH1A1HTT | |
| SCHEMBL11232508 | 0.81 | KMT2A (0.70) | NAAAEGFREPHX1ALDH1A1HTT | |
| SCHEMBL11224571 | 0.80 | NAAA (0.51) | NAAAEGFREPHX1ALDH1A1HTT | |
| SCHEMBL11224100 | 0.78 | NAAA (0.47) | NAAAEPHX1ALDH1A1HTTLMNA | |
| SCHEMBL11234894 | 0.78 | LMNA (0.47) | ALDH1A1HTTMEN1LMNAHPGD | |
| SCHEMBL11234890 | 0.78 | LMNA (0.47) | ALDH1A1HTTMEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342781-A | PREVENTING AND TREATING ALLERGIC BRONCHIAL ASTHMA, RHINITIS AND SKIN DISORDERS | PFIZER INC. (US) | 1982-08-03 | — | — | US | disclosed |