Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222408 | 0.87 | NAAA (0.55) | NAAAEGFRHTTLMNAMAPT | |
| SCHEMBL11218806 | 0.87 | NAAA (0.55) | NAAAEGFRHTTLMNAMAPT | |
| SCHEMBL11224412 | 0.87 | NAAA (0.55) | NAAAEGFRHTTLMNAMAPT | |
| SCHEMBL11220069 | 0.87 | NAAA (0.55) | NAAAEGFRHTTLMNAMAPT | |
| SCHEMBL11218890 | 0.87 | NAAA (0.55) | NAAAEGFRHTTLMNAMAPT | |
| SCHEMBL11099991 | 0.84 | ALDH1A1 (0.47) | NAAAEGFRLMNACYP2D6CYP2C9 | |
| SCHEMBL11099989 | 0.84 | ALDH1A1 (0.47) | NAAAEGFRLMNACYP2D6CYP2C9 | |
| SCHEMBL11227851 | 0.82 | MAPT (0.58) | NAAAEGFRHTTLMNAMAPT | |
| SCHEMBL11216901 | 0.80 | EPHX1 (0.48) | NAAAHTTLMNAMAPTNPSR1 | |
| SCHEMBL11224454 | 0.80 | NAAA (0.55) | NAAAEGFRHTTLMNAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342781-A | PREVENTING AND TREATING ALLERGIC BRONCHIAL ASTHMA, RHINITIS AND SKIN DISORDERS | PFIZER INC. (US) | 1982-08-03 | — | — | US | disclosed |