Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 12/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 11/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15001063 | 0.94 | CRHBP (0.45) | CRHBPCRHR2HCRTR2HCRTR1HTR2A | |
| SCHEMBL17376705 | 0.89 | HCRTR2 (0.43) | HCRTR2HCRTR1 | |
| SCHEMBL17382579 | 0.81 | TP53 (0.46) | HCRTR2HCRTR1 | |
| SCHEMBL11229583 | 0.81 | HCRTR1 (0.39) | HCRTR2HCRTR1 | |
| SCHEMBL11228395 | 0.80 | CRHBP (0.38) | CRHBPCRHR2HCRTR2HCRTR1 | |
| SCHEMBL15001062 | 0.79 | CRHBP (0.43) | CRHBPCRHR2HCRTR2HCRTR1HTR2A | |
| SCHEMBL15822053 | 0.76 | CRHBP (0.38) | CRHBPCRHR2HCRTR2HCRTR1 | |
| SCHEMBL15821813 | 0.76 | CRHBP (0.41) | CRHBPCRHR2HCRTR2HCRTR1HTR2A | |
| SCHEMBL15821759 | 0.76 | CA1 (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL15839529 | 0.76 | KMT2A (0.32) | CRHBPCRHR2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007243-B1 | 2-ARYL-1,3-CYCLOHEXANEDIONE COMPOUNDS AND ALKALI METAL SALTS, AMMONIUM SALTS AND ENOL ESTERS THEREOF, COMPOSITION AND METHOD OF CONTROLLING ACARINA ECTOPARASITES ON WARMBLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4257858-A | REACTING A CYCLOHEXA-1,3-DIONE-2-DIAZIDE WITH AN ARYL COMPOUND | UNION CARBIDE CORPORATION (US) | 1981-03-24 | — | — | US | disclosed |
| US-4256658-A | CYCLIZATION, BASIC CATALYST | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4256657-A | CYCLIZATION, ACID CATALYST | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4256659-A | Method of preparing 2-aryl-1,3-cyclohexanedione compounds | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4209532-A | Biocidal 2-aryl-1,3-cyclohexane dione compounds and alkali metal and ammonium salts thereof | UNION CARBIDE CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| EP-0007243-A1 | 2-Aryl-1,3-cyclohexanedione compounds and alkali metal salts, ammonium salts and enol esters thereof, composition and method of controlling acarina ectoparasites on warmblooded animals | UNION CARBIDE CORPORATION (US) | 1980-01-23 | — | — | EP | disclosed |
| US-4175135-A | Method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animal an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound, and alkali metal salts, ammonium salts and enol esters thereof | UNION CARBIDE CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |