Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 8/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11224539 | 0.89 | CRHBP (0.43) | HCRTR2HCRTR1 | |
| SCHEMBL11229583 | 0.89 | HCRTR1 (0.39) | HCRTR2HCRTR1ACHEPOLL | |
| SCHEMBL17382579 | 0.89 | TP53 (0.46) | HCRTR2HCRTR1ACHEPOLL | |
| SCHEMBL15001063 | 0.81 | CRHBP (0.45) | HCRTR2HCRTR1ACHEPOLL | |
| SCHEMBL17376649 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL21985342 | 0.74 | HCRTR1 (0.46) | HCRTR2HCRTR1POLL | |
| SCHEMBL16937274 | 0.71 | DDB1 (0.52) | — | |
| SCHEMBL4531809 | 0.70 | PDE4A (0.50) | HCRTR2HCRTR1ACHEPOLLDRD2 | |
| SCHEMBL9052842 | 0.70 | DRD2 (0.45) | HCRTR2HCRTR1ACHEDRD2 | |
| SCHEMBL15821759 | 0.69 | CA1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458958-B | Herbicidal propynyl-phenyl compounds | 先正达参股股份有限公司 | 2020-07-10 | — | — | CN | disclosed |
| US-10662138-B2 | Herbicidal propynyl-phenyl compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-26 | — | — | US | disclosed |
| US-10662138-B2 | Herbicidal propynyl-phenyl compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-26 | — | — | US | disclosed |
| EP-3160950-B1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | disclosed |
| EP-3160950-B1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | disclosed |
| US-20170183281-A1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-29 | — | — | US | disclosed |
| US-20170183281-A1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-29 | — | — | US | disclosed |
| US-20170183281-A1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-29 | — | — | US | disclosed |
| EP-3160950-A1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | Syngenta Participations AG (CH) | 2017-05-03 | — | — | EP | disclosed |
| WO-2015197468-A1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662138-B2 | Herbicidal propynyl-phenyl compounds | CBR3, CBR1, CNPY3 | HCRTR2 403/4885HCRTR1 94/4885ACHE 1073/4885 |
| US-20170183281-A1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | CBR3, CBR1, CNPY3 | HCRTR2 403/4885HCRTR1 94/4885ACHE 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.