SCHEMBL11224581

SCHEMBL11224581

C=CC(=O)CCCC(=C)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.45
HSD17B10 Q99714 1/20 0.45
ALDH1A1 P00352 3/20 0.37
TSHR P16473 3/20 0.37
MAPT P10636 2/20 0.35
TBXAS1 P24557 2/20 0.35
LMNA P02545 1/20 0.33
TET2 Q6N021 4/20 0.32
TET3 O43151 1/20 0.32
TET1 Q8NFU7 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
GRM1 Q13255 1/20 0.31
GRM2 Q14416 1/20 0.31
ABCC4 O15439 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22902969 0.95 ALOX15 (0.45) ALOX15HSD17B10ALDH1A1TSHRMAPT
SCHEMBL17315005 0.86 ALOX15 (0.48) ALOX15HSD17B10ALDH1A1TSHRTBXAS1
SCHEMBL1988202 0.83 ALDH1A1 (0.50) ALDH1A1TSHRMAPTLMNASLC22A6
SCHEMBL7989948 0.83 SLC22A6 (0.44) ALOX15HSD17B10TSHRTBXAS1LMNA
SCHEMBL8032580 0.78 SLC22A6 (0.58) ALDH1A1TSHRMAPTLMNASLC22A6
SCHEMBL6557587 0.77 ALDH1A1 (0.50) ALDH1A1TSHRMAPTLMNAABCC4
SCHEMBL2025802 0.77 TBXAS1 (0.47) ALOX15HSD17B10TSHRTBXAS1LMNA
Acrylic Acid SCHEMBL1411416 0.76 ALOX15 (0.54) ALOX15HSD17B10ALDH1A1TSHRMAPT
SCHEMBL33625 0.75 SLC22A6 (0.61) ALOX15HSD17B10ALDH1A1TSHRMAPT
SCHEMBL23631357 0.75 TSHR (0.48) ALDH1A1TSHRMAPTLMNAABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4229431-A IN SITU POLYMERIZATION LEE PHARMACEUTICALS (US) 1980-10-21 US claimed
US-4104333-A COMPOSITIONS CONTAINING CROSSLINKING MONOMERS, MONOACRYLATES, INITIATORS AND ACCELERATORS LEE PHARMACEUTICALS (US) 1978-08-01 US claimed
US-4340532-A CURABLE ORTHODONTIC COMPOSITION LEE PHARMACEUTICALS, INC. (US) 1982-07-20 US disclosed
US-4340529-A CURABLE ACRYLATE PRIMER LEE PHARMACEUTICALS, INC. (US) 1982-07-20 US disclosed
US-4260701-A Formulation for self-curing artificial fingernails containing methoxyethyl methacrylate LEE PHARMACEUTICALS (US) 1981-04-07 US disclosed
US-4229431-A IN SITU POLYMERIZATION LEE PHARMACEUTICALS (US) 1980-10-21 US disclosed
US-4104333-A COMPOSITIONS CONTAINING CROSSLINKING MONOMERS, MONOACRYLATES, INITIATORS AND ACCELERATORS LEE PHARMACEUTICALS (US) 1978-08-01 US disclosed