SCHEMBL11224853

SCHEMBL11224853

CC(CN)NCC(O)COC(C)C

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CASR P41180 1/20 0.36
ADRB2 P07550 4/20 0.36
ADRB1 P08588 4/20 0.36
ADRB3 P13945 4/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP2D6 P10635 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
KDM4E B2RXH2 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11222567 0.82 MAPT (0.41) ADRB2ADRB1ADRB3MEN1KMT2A
SCHEMBL11236751 0.81 KDM4E (0.44) ADRB2ADRB1ADRB3MEN1KMT2A
SCHEMBL23418071 0.79 ADRB2 (0.50) ADRB2ADRB1ADRB3CYP2D6
SCHEMBL12122746 0.79 ADRB2 (0.50) ADRB2ADRB1ADRB3CYP2D6
SCHEMBL11235909 0.78 HSD17B10 (0.48) CASRADRB2ADRB1MEN1KMT2A
SCHEMBL11232890 0.77 CASR (0.36) CASRADRB2ADRB1ADRB3MEN1
SCHEMBL15042356 0.77
SCHEMBL21743243 0.77
SCHEMBL3726548 0.77
SCHEMBL2431055 0.75 HPGD (0.34) HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4315846-A FUNGICIDES TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1982-02-16 US disclosed
EP-0037861-A1 Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1981-10-21 EP disclosed