SCHEMBL2431055

SCHEMBL2431055

CCC(O)CNC(C)CN

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
TSHR P16473 1/20 0.33
POLB P06746 1/20 0.32
GABRR1 P24046 2/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7050022 0.83 HPGD (0.44) HPGDHTTTSHRPOLB
SCHEMBL13934087 0.83 HPGD (0.44) HPGDHTTTSHRPOLB
SCHEMBL11418856 0.82 LMNA (0.35) GABRR1LMNA
SCHEMBL11236751 0.79 KDM4E (0.44) HPGDHTTPOLB
SCHEMBL1247692 0.78
SCHEMBL31589015 0.78
SCHEMBL15468368 0.77 ADRB2 (0.39) HPGDHTTTSHRPOLBLMNA
SCHEMBL11222567 0.77 MAPT (0.41) HPGDHTTPOLB
SCHEMBL11235909 0.77 HSD17B10 (0.48) HPGDHTTPOLB
SCHEMBL8376757 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110232489-A1 METHOD TO DECREASE DECOMPOSITION PRODUCTS IN SOLUTIONS THAT ABSORB ACIDIC GASES SUCH AS CARBON DIOXIDE AND THE LIKE IN THE PRESENCE OF OXYGEN HUNTSMAN PETROCHEMICAL LLC (US) 2011-09-29 US claimed
US-7169268-B2 Storage stability; discoloration inhibition; mixing with ethyleneamine; distillation HUNTSMAN PETROCHEMICAL CORPORATION (US) 2007-01-30 US claimed
US-20040000471-A1 Color stabilization of amines HUNTSMAN PETROCHEMICAL CORPORATION (US) 2004-01-01 US claimed
EP-1362262-A1 SEMICONDUCTOR DEVELOPING AGENT HUNTSMAN PETROCHEMICAL CORPORATION (US) 2003-11-19 EP claimed
WO-2002069052-A1 SEMICONDUCTOR DEVELOPING AGENT HUNTSMAN PETROCHEMICAL CORPORATION (US) 2002-09-06 WO claimed
US-6340559-B1 IN THE MANUFACTURE OF INTEGRATED CIRCUITS HUNTSMAN PETROCHEMICAL CORPORATION 2002-01-22 US claimed
EP-2373760-B1 DECREASED PRESENCE OF AMINE-DERIVED CONTAMINANTS IN- AND/OR DEGRADATION OF AMINE SOLVENT SOLUTIONS HUNTSMAN PETROCHEMICAL LLC (US) 2016-08-03 EP disclosed
US-8945280-B2 Method to decrease decomposition products in solutions that absorb acidic gases such as carbon dioxide and the like in the presence of oxygen HUNTSMAN PETROCHEMICAL LLC (US) 2015-02-03 US disclosed
US-20110232489-A1 METHOD TO DECREASE DECOMPOSITION PRODUCTS IN SOLUTIONS THAT ABSORB ACIDIC GASES SUCH AS CARBON DIOXIDE AND THE LIKE IN THE PRESENCE OF OXYGEN HUNTSMAN PETROCHEMICAL LLC (US) 2011-09-29 US disclosed
US-7169268-B2 Storage stability; discoloration inhibition; mixing with ethyleneamine; distillation HUNTSMAN PETROCHEMICAL CORPORATION (US) 2007-01-30 US disclosed
US-20040000471-A1 Color stabilization of amines HUNTSMAN PETROCHEMICAL CORPORATION (US) 2004-01-01 US disclosed
EP-1362262-A1 SEMICONDUCTOR DEVELOPING AGENT HUNTSMAN PETROCHEMICAL CORPORATION (US) 2003-11-19 EP disclosed
WO-2002069052-A1 SEMICONDUCTOR DEVELOPING AGENT HUNTSMAN PETROCHEMICAL CORPORATION (US) 2002-09-06 WO disclosed
US-6340559-B1 IN THE MANUFACTURE OF INTEGRATED CIRCUITS HUNTSMAN PETROCHEMICAL CORPORATION 2002-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040000471-A1 Color stabilization of amines PNMT, TES, EMD HPGD 2268/4885HTT 600/4885TSHR 3088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.