SCHEMBL11235909

SCHEMBL11235909

CCCOCC(O)CNC(C)CN

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.48
HTT P42858 2/20 0.47
POLB P06746 1/20 0.45
TDP1 Q9NUW8 1/20 0.42
HPGD P15428 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ADRB2 P07550 2/20 0.38
ADRB1 P08588 2/20 0.38
USP2 O75604 1/20 0.37
CASR P41180 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11233623 0.92 HTT (0.56) HSD17B10HTTPOLBHPGDKDM4E
SCHEMBL11236751 0.89 KDM4E (0.44) HTTPOLBHPGDKDM4EADRB2
SCHEMBL11231094 0.89 HTT (0.66) HSD17B10HTTPOLBHPGDUSP2
SCHEMBL11222567 0.83 MAPT (0.41) HTTPOLBHPGDADRB2ADRB1
SCHEMBL15489273 0.79 POLB (0.46) HSD17B10HTTPOLBTDP1HPGD
SCHEMBL11224853 0.78 CASR (0.36) HTTHPGDKDM4EADRB2ADRB1
SCHEMBL17810294 0.77 POLB (0.57) HSD17B10HTTPOLBHPGDKDM4E
SCHEMBL2431055 0.77 HPGD (0.34) HTTPOLBHPGD
SCHEMBL11233531 0.76 KDM4E (0.52) HSD17B10HTTPOLBTDP1HPGD
SCHEMBL5430125 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4315846-A FUNGICIDES TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1982-02-16 US disclosed
EP-0037861-A1 Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1981-10-21 EP disclosed