Tetraethylene Glycol

Tetraethylene Glycol

SCHEMBL11224926

C=C(C)C(=O)OCCOC(=O)C(=C)C.C=C(C)C(=O)OCCOC(=O)C(=C)C.C=COCCOCCOC=C.OCCOCCOCCOCCO

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.54
TSHR P16473 8/20 0.41
ALDH1A1 P00352 5/20 0.39
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HTT P42858 2/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPK1 P28482 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MAPT P10636 1/20 0.31
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36623 0.93 THRB (0.61) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL12804318 0.93 THRB (0.61) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL2831369 0.93 THRB (0.61) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL12805165 0.93 THRB (0.61) THRBTSHRALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL29216884 0.89 THRB (0.56) THRBTSHRALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL30912178 0.89 THRB (0.56) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL2367411 0.88 THRB (0.68) THRBTSHRALDH1A1TP53HIF1A
Tetraethylene Glycol SCHEMBL8659912 0.88 THRB (0.68) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL61385 0.88 THRB (0.68) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL2880688 0.88 THRB (0.57) THRBTSHRALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0042406-A4 PHOTOPOLYMERIZED HYDROPHILIC FILMSOR FIBERS OF ACRYLIC ACID AND POLYFUNCTIONAL CROSS-LINKING AGENTS. GOODRICH CO B F (US) 1982-01-26 EP claimed
EP-0042406-A1 PHOTOPOLYMERIZED HYDROPHILIC FILMSOR FIBERS OF ACRYLIC ACID AND POLYFUNCTIONAL CROSS-LINKING AGENTS. GOODRICH CO B F (US) 1981-12-30 EP claimed
WO-1981001850-A1 PHOTOPOLYMERIZED HYDROPHILIC INTERPOLYMERS OF ACRYLIC ACID AND POLYFUNCTIONAL CROSS-LINKING AGENTS GOODRICH CO B F (US) 1981-07-09 WO claimed