Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887159 | 0.88 | GAA (0.68) | GAALMNAPOLBSTING1NPC1 | |
| SCHEMBL28342529 | 0.88 | GAA (0.56) | GAALMNAPOLBSTING1NPC1 | |
| SCHEMBL965934 | 0.85 | GAA (0.60) | GAALMNAPOLBKDM4EALDH1A1 | |
| SCHEMBL13064423 | 0.83 | GAA (0.54) | GAALMNAPOLBSTING1KDM4E | |
| SCHEMBL13936345 | 0.82 | POLB (0.58) | GAALMNAPOLBSTING1ALDH1A1 | |
| SCHEMBL353314 | 0.82 | GAA (0.56) | GAALMNAPOLBSTING1NPC1 | |
| SCHEMBL19182678 | 0.82 | GAA (0.56) | GAALMNAPOLBSTING1NPC1 | |
| SCHEMBL970933 | 0.81 | GAA (0.55) | GAALMNAPOLBSTING1NPC1 | |
| SCHEMBL4556189 | 0.81 | GAA (0.55) | GAALMNAPOLBSTING1KDM4E | |
| SCHEMBL17350744 | 0.81 | GAA (0.55) | GAALMNAPOLBSTING1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597252-B1 | PYRIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | BAYER SAS (FR) | 2011-02-09 | — | — | EP | disclosed |
| US-7754741-B2 | Pyridine derivatives as fungicidal compounds | BAYER CROPSCIENCE S.A. (FR) | 2010-07-13 | — | — | US | disclosed |
| US-7754741-B2 | Pyridine derivatives as fungicidal compounds | BAYER CROPSCIENCE S.A. (FR) | 2010-07-13 | — | — | US | disclosed |
| US-7754741-B2 | Pyridine derivatives as fungicidal compounds | BAYER CROPSCIENCE S.A. (FR) | 2010-07-13 | — | — | US | disclosed |
| CN-100402525-C | Pyridine derivatives as fungicidal compounds | BAYER CROPSCIENCE SA (FR) | 2008-07-16 | — | — | CN | disclosed |
| CN-1751039-A | Pyridine derivatives as fungicidal compounds | BAYER CROPSCIENCE SA (FR) | 2006-03-22 | — | — | CN | disclosed |
| US-20060052366-A1 | Pyridine derivatives as fungicidal compounds | BAYER SAS (FR) | 2006-03-09 | — | — | US | disclosed |
| EP-1597252-A1 | PYRIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | Bayer CropScience S.A. (FR) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004074280-A1 | PYRIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | BAYER CROPSCIENCE SA (FR) | 2004-09-02 | — | — | WO | disclosed |
| EP-1449841-A1 | New fungicidal compounds | Bayer CropScience SA (FR) | 2004-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052366-A1 | Pyridine derivatives as fungicidal compounds | CYP3A7, CYP4B1, CYP4X1 | GAA 80/4885LMNA 4207/4885POLB 4012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.