Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.36 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19182678 | 1.00 | GAA (0.56) | GAALMNAPOLBSTING1PSEN1 | |
| Hydrochloric Acid SCHEMBL8355477 | 0.98 | GAA (0.55) | GAALMNAPOLBSTING1PSEN1 | |
| SCHEMBL2347739 | 0.86 | GAA (0.47) | GAALMNAPOLBSTING1PSEN1 | |
| SCHEMBL1194663 | 0.86 | LMNA (0.46) | GAALMNAPOLBSTING1PKM | |
| SCHEMBL2903444 | 0.86 | LMNA (0.46) | GAALMNAPOLBSTING1PSEN1 | |
| SCHEMBL13936345 | 0.85 | POLB (0.58) | GAALMNAPOLBSTING1PSEN1 | |
| SCHEMBL1195430 | 0.84 | LMNA (0.45) | GAALMNAPOLBSTING1PKM | |
| SCHEMBL17350744 | 0.84 | GAA (0.55) | GAALMNAPOLBSTING1PSEN1 | |
| SCHEMBL4556189 | 0.84 | GAA (0.55) | GAALMNAPOLBSTING1PSEN1 | |
| SCHEMBL970933 | 0.84 | GAA (0.55) | GAALMNAPOLBSTING1PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 522 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117887086-A | Application of halogen functionalized metal organic framework material in storage and delivery of fluorine-containing electron special gas | 华为技术有限公司 | 2024-04-16 | — | — | CN | claimed |
| WO-2024074141-A1 | POROUS MATERIAL AND APPLICATION THEREOF | 华为技术有限公司 | 2024-04-11 | — | — | WO | claimed |
| CN-114957124-B | 3- (trifluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2023-11-07 | — | — | CN | claimed |
| CN-116969930-A | Thiazole ring-containing pyrazole carboxamide derivative and preparation method and application thereof | 安徽农业大学 | 2023-10-31 | — | — | CN | claimed |
| CN-113880762-B | Triacylamine derivatives containing 1,8-naphthalimide as well as preparation method and application thereof | 河北农业大学 | 2023-02-21 | — | — | CN | claimed |
| CN-115260174-A | 5- (pyrazole-4-yl) -1,2, 4-oxadiazole substituted benzamide compounds and preparation method and application thereof | 浙江工业大学 | 2022-11-01 | — | — | CN | claimed |
| CN-114957124-A | 3- (trifluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2022-08-30 | — | — | CN | claimed |
| CN-114195715-A | Process for preparing 1-methyl-3-difluoromethyl-4-pyrazolic acid and 1-methyl-3-trifluoromethyl-4-pyrazolic acid | 福建永晶科技股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| US-20190070149-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2019-03-07 | — | — | US | claimed |
| CN-107033083-A | A kind of acyl urea compound for containing the trifluoromethyl 1H pyrrazole structures of 1 methyl 3 and its preparation method and application | 浙江工业大学 | 2017-08-11 | — | — | CN | claimed |
| WO-2010049405-A1 | METHOD FOR IMPROVING PLANT HEALTH | BASF SE (DE) | 2010-05-06 | — | — | WO | claimed |
| US-20090197935-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2009-08-06 | — | — | US | claimed |
| WO-2009015208-A1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | REPLIDYNE, INC. (US) | 2009-01-29 | — | — | WO | claimed |
| EP-2001299-A2 | FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS | Bayer CropScience Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | claimed |
| EP-1902025-A1 | KINASE INHIBITORS | Allergan, Inc. (US) | 2008-03-26 | — | — | EP | claimed |
| WO-2007110173-A2 | FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2007-10-04 | — | — | WO | claimed |
| EP-1813152-A1 | Fungicidal mixture based on 3,4-disubstituted biphenylanilides | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-01 | — | — | EP | claimed |
| US-20070032478-A1 | Kinase Inhibitors | ALLERGAN, INC. | 2007-02-08 | — | — | US | claimed |
| WO-2007008895-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2007-01-18 | — | — | WO | claimed |
| CN-1245384-C | Carboxamides as fungicides in agriculture | SYNGENTA PARTICIPATIONS AG (CH) | 2006-03-15 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190070149-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | HTR5A, HTR2A, HTR1A | GAA 1403/4885LMNA 2106/4885POLB 4237/4885 |
| US-20090197935-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | HTR5A, HTR2A, HTR1A | GAA 2043/4885LMNA 1736/4885POLB 4165/4885 |
| US-20070032478-A1 | Kinase Inhibitors | ABL1, LCK, ERBB2 | GAA 1455/4885LMNA 4604/4885POLB 1863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.