Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGES2 | Q9H7Z7 | 9/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122528 | 1.00 | SCN9A (0.32) | SCN9APKMKMT2APTGES2 | |
| SCHEMBL1148587 | 0.68 | CA1 (0.37) | SCN9A | |
| SCHEMBL1122637 | 0.67 | FDPS (0.33) | PKMKMT2APTGES2 | |
| SCHEMBL1122635 | 0.67 | FDPS (0.33) | PKMKMT2APTGES2 | |
| SCHEMBL1324206 | 0.66 | VCP (0.38) | PKMKMT2APTGES2 | |
| SCHEMBL1324203 | 0.66 | VCP (0.38) | PKMKMT2APTGES2 | |
| SCHEMBL1324942 | 0.66 | VCP (0.38) | PKMKMT2APTGES2 | |
| SCHEMBL9959892 | 0.61 | GAA (0.53) | PKMKMT2A | |
| SCHEMBL1005929 | 0.59 | — | — | |
| SCHEMBL4790981 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379508-B9 | N-(ARYL)-2-ARYLETHENESULFONAMIDES AND THERAPEUTIC USES THEREOF | UNIV TEMPLE (US) | 2011-02-09 | — | — | EP | disclosed |