Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122635 | 1.00 | FDPS (0.33) | FDPSADRA2AADRA2CPKMKMT2A | |
| SCHEMBL19708649 | 0.68 | FDPS (0.42) | FDPSADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL28882502 | 0.68 | FDPS (0.46) | FDPSADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL1122530 | 0.67 | SCN9A (0.32) | PKMKMT2APTGES2 | |
| SCHEMBL1122528 | 0.67 | SCN9A (0.32) | PKMKMT2APTGES2 | |
| SCHEMBL1324942 | 0.66 | VCP (0.38) | PKMKMT2APTGES2 | |
| SCHEMBL1324203 | 0.66 | VCP (0.38) | PKMKMT2APTGES2 | |
| SCHEMBL1324206 | 0.66 | VCP (0.38) | PKMKMT2APTGES2 | |
| SCHEMBL19700365 | 0.64 | FDPS (0.39) | FDPSADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL20936102 | 0.64 | FDPS (0.42) | FDPSADRA2AADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379508-B9 | N-(ARYL)-2-ARYLETHENESULFONAMIDES AND THERAPEUTIC USES THEREOF | UNIV TEMPLE (US) | 2011-02-09 | — | — | EP | disclosed |
| EP-1379508-B1 | N-(ARYL)-2-ARYLETHENESULFONAMIDES AND THERAPEUTIC USES THEREOF | UNIV TEMPLE (US) | 2010-09-01 | — | — | EP | disclosed |