SCHEMBL1122552

SCHEMBL1122552

CC(=O)Nc1cccc2c(O)cccc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.58
RXFP1 Q9HBX9 1/20 0.56
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.56
ALDH1A1 P00352 3/20 0.55
GAA P10253 1/20 0.55
CDC25B P30305 2/20 0.51
KCNJ11 Q14654 1/20 0.51
IDO1 P14902 2/20 0.50
HPGD P15428 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MAPT P10636 1/20 0.50
CHEK1 O14757 1/20 0.50
DAPK3 O43293 1/20 0.50
PRKD3 O94806 1/20 0.50
MAP4K4 O95819 1/20 0.50
NTRK1 P04629 1/20 0.50
RET P07949 1/20 0.50
MET P08581 1/20 0.50
PIM1 P11309 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1900214 0.90 RXFP1 (0.66) RXFP1KMT2AMEN1ALDH1A1GAA
SCHEMBL590479 0.89 RXFP1 (0.66) RXFP1KMT2ACDC25BIDO1KDM4E
SCHEMBL20498498 0.82 TRPV1 (0.59) TRPV1KMT2AMEN1ALDH1A1GAA
SCHEMBL21387943 0.82 RXFP1 (0.58) RXFP1KMT2AMEN1ALDH1A1GAA
SCHEMBL9359137 0.82 TRPV1 (0.52) TRPV1RXFP1KMT2AMEN1ALDH1A1
SCHEMBL9126461 0.81 TRPV1 (0.55) TRPV1KMT2AMEN1ALDH1A1GAA
SCHEMBL1805658 0.81 RXFP1 (0.56) RXFP1KMT2AMEN1ALDH1A1HPGD
SCHEMBL8923243 0.81 ALDH1A1 (0.66) RXFP1KMT2AMEN1ALDH1A1HPGD
SCHEMBL19771462 0.80 TRPV1 (0.54) TRPV1KMT2AMEN1ALDH1A1GAA
SCHEMBL26885099 0.80 IDO1 (0.62) TRPV1ALDH1A1GAACDC25BIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8859711-B2 Method for preparing wholly aromatic liquid crystalline polyester amide resin and method for preparing wholly aromatic liquid crystalline polyester amide resin compound SAMSUNG FINE CHEMICALS CO., LTD. (KR) 2014-10-14 US claimed
EP-2644639-A2 METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN AND METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN COMPOUND Samsung Fine Chemicals Co., Ltd. (KR) 2013-10-02 EP claimed
US-20130231453-A1 METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN AND METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN COMPOUND SAMSUNG FINE CHEMICALS CO., LTD. (KR) 2013-09-05 US claimed
US-8859711-B2 Method for preparing wholly aromatic liquid crystalline polyester amide resin and method for preparing wholly aromatic liquid crystalline polyester amide resin compound SAMSUNG FINE CHEMICALS CO., LTD. (KR) 2014-10-14 US disclosed
EP-2644639-A2 METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN AND METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN COMPOUND Samsung Fine Chemicals Co., Ltd. (KR) 2013-10-02 EP disclosed
US-20130231453-A1 METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN AND METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN COMPOUND SAMSUNG FINE CHEMICALS CO., LTD. (KR) 2013-09-05 US disclosed
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed
EP-1831184-B1 PYRAZINES AND PYRIDINES AND DERIVATIVES THEREOF AS THERAPEUTIC COMPOUNDS WELLCOME TRUST LTD (GB) 2011-02-09 EP disclosed
EP-1831184-B1 PYRAZINES AND PYRIDINES AND DERIVATIVES THEREOF AS THERAPEUTIC COMPOUNDS WELLCOME TRUST LTD (GB) 2011-02-09 EP disclosed
US-7737152-B2 6-carboaryl-oxy-pyrazin-2-yl-carboaryl-amines and compositions comprising said compounds THE WELLCOME TRUST LIMITED (GB) 2010-06-15 US disclosed
EP-0603953-A1 Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods Johnson & Johnson Clinical Diagnostics, Inc. (US) 1994-06-29 EP disclosed
EP-0603954-A2 Analytical element and immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer Johnson & Johnson Clinical Diagnostics, Inc. (US) 1994-06-29 EP disclosed
EP-0574090-A1 One equivalent couplers and low pKa release dyes EASTMAN KODAK COMPANY (US) 1993-12-15 EP disclosed
US-4703111-A Water-soluble compounds containing one or two (nitrophenylamino)-phenylamino-chlorotriazinylamino groups, the nitrophenylamino being additionally substituted by a fiber-reactive group of the vinylsulfonyl series, suitable as dyestuffs HOECHST AKTIENGESELLSCHAFT A CORP. OF GERMANY (DE) 1987-10-27 US disclosed
EP-0148201-A4 NAPHTALENE AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMA CEUTICAL USES. RORER INTERNAT OVERSEAS INC (US) 1985-09-26 EP disclosed
EP-0148201-A1 NAPHTALENE AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMA CEUTICAL USES RORER INTERNATIONAL (OVERSEAS) INC. (US) 1985-07-17 EP disclosed
US-4504568-A Sensitive silver halide photothermographic materials for producing dye images EASTMAN KODAK COMPANY (US) 1985-03-12 US disclosed
WO-1984004245-A1 NAPHTALENE AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMA CEUTICAL USES RORER INT OVERSEAS (US) 1984-11-08 WO disclosed
US-3966704-A Naphthylazo naphthyl copper complex dyestuffs HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 TRPV1 3166/4885RXFP1 1645/4885KMT2A 1224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.