SCHEMBL11225682

SCHEMBL11225682

C=C(CC(Cl)(Cl)Cl)c1cccc(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.44
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
ERCC5 P28715 1/20 0.41
FEN1 P39748 1/20 0.41
SLC6A2 P23975 4/20 0.41
SLC6A3 Q01959 3/20 0.41
CHRNA1 P02708 1/20 0.41
CHRNG P07510 1/20 0.41
ITGA5 P08648 1/20 0.41
CHRNB1 P11230 1/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNB4 P30926 1/20 0.41
SLC6A4 P31645 1/20 0.41
CHRNA3 P32297 1/20 0.41
CYP2C19 P33261 1/20 0.41
HRH1 P35367 1/20 0.41
CHRNA7 P36544 1/20 0.41
OPRK1 P41145 1/20 0.41
CHRNA4 P43681 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10563520 0.84 PARP1 (0.41) PARP1MAOAMAOBERCC5FEN1
SCHEMBL9418620 0.80 TPMT (0.38) MAOAMAOBTSHRRAB9A
SCHEMBL11225717 0.80 C1S (0.43) PARP1CYP2C19ALDH1A1SMN1; SMN2MEN1
SCHEMBL9055041 0.79 PARP1 (0.48) PARP1MAOAMAOBERCC5FEN1
SCHEMBL28604413 0.79 PARP1 (0.48) PARP1MAOAMAOBERCC5FEN1
SCHEMBL10486356 0.78 MAOA (0.47) MAOAMAOBALDH1A1SMN1; SMN2TSHR
SCHEMBL2015776 0.77 MAOA (0.48) PARP1MAOAMAOBERCC5FEN1
SCHEMBL21783054 0.77 PARP1 (0.47) PARP1MAOAMAOBERCC5FEN1
SCHEMBL2662195 0.76 PARP1 (0.46) PARP1MAOAMAOBERCC5FEN1
SCHEMBL8608642 0.75 MAOA (0.41) PARP1MAOAMAOBERCC5FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4324581-A ALPHA-TRICHLOROETHYL-M-HALOSTYRENE THE DOW CHEMICAL COMPANY (US) 1982-04-13 US claimed
US-4086081-A PREEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-25 US claimed
US-4324581-A ALPHA-TRICHLOROETHYL-M-HALOSTYRENE THE DOW CHEMICAL COMPANY (US) 1982-04-13 US disclosed
US-4324581-A ALPHA-TRICHLOROETHYL-M-HALOSTYRENE THE DOW CHEMICAL COMPANY (US) 1982-04-13 US disclosed
US-4086081-A PREEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-25 US disclosed
US-4086081-A PREEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-25 US disclosed