SCHEMBL10486356

SCHEMBL10486356

C=C(CC(Cl)(Cl)Cl)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.47
MAOB P27338 6/20 0.47
DAO P14920 1/20 0.39
TSHR P16473 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
ALDH1A1 P00352 3/20 0.37
MAPK1 P28482 3/20 0.37
HIF1A Q16665 2/20 0.37
TRPA1 O75762 1/20 0.37
GSK3B P49841 1/20 0.37
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
CES1 P23141 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8676203 0.83 MAOA (0.44) MAOAMAOBALDH1A1MAPK1HIF1A
SCHEMBL11203095 0.78 NAPRT (0.41) NAPRTALDH1A1HIF1AKDM4EMEN1
Carbon Tetrachloride SCHEMBL28327161 0.78 TAAR1 (0.44) MAOAMAOBTSHRALDH1A1HIF1A
SCHEMBL11225682 0.78 PARP1 (0.44) MAOAMAOBTSHRALDH1A1KDM4E
SCHEMBL2399414 0.77 MAOA (0.47) MAOAMAOBALDH1A1HIF1AMAPT
SCHEMBL7792764 0.77 ESR1 (0.47) MAOAMAOBMAPK1MAPTKDM4E
SCHEMBL11225717 0.77 C1S (0.43) ALDH1A1MEN1HPGDKMT2ASMN1; SMN2
SCHEMBL11285343 0.76 TSHR (0.42) DAOTSHRNAPRTALDH1A1MAPK1
SCHEMBL14921 0.74 TAAR1 (0.48) MAOAMAOBALDH1A1MAPK1HIF1A
SCHEMBL15851 0.73 ALDH1A1 (0.52) MAOAMAOBDAOTSHRNAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
US-4818536-A HYDROPHOBIC AGRICULTURE CHEMICAL AND POLYMER, EMULSIFIER, AND SOLVENT; STORAGE STABILITY, NONAQUEOUS, ON-SITE PREPARATION THE DOW CHEMICAL COMPANY (US) 1989-04-04 US claimed
WO-2026101910-A1 FUNGICIDAL FORMULATIONS CONTAINING ARYL AMIDINES AND METHODS OF USE CORTEVA AGRISCIENCE LLC (US) 2026-05-15 WO disclosed
US-12616203-B2 Use of 3-isoxazolidinones compounds as selective herbicides FMC CORPORATION (US) 2026-05-05 US disclosed
US-12509452-B2 Substituted-isoxazoline-containing aromatic compound, preparation method therefor, herbicidal composition and use thereof QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2025-12-30 US disclosed
EP-4666856-A2 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Corteva Agriscience LLC (US) 2025-12-24 EP disclosed
EP-4667459-A1 BENZENE RING-SUBSTITUTED PYRIMIDINE CARBOXYLIC ACID COMPOUND, AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION COMPRISING SAME, AND USE THEREOF Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) 2025-12-24 EP disclosed
US-12497365-B2 4-pyridinyl formamide compound or derivative thereof, preparation method therefor, herbicidal composition and use thereof QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2025-12-16 US disclosed
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2025-12-09 US disclosed
US-4222767-A Certain herbicidal sulfonates and sulfamates FISONS LIMITED (GB) 1980-09-16 US disclosed
EP-0007719-A2 Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives FBC LIMITED (GB) 1980-02-06 EP disclosed
US-4183741-A POSTEMERGENCE FISONS LIMITED (GB) 1980-01-15 US disclosed
US-4163846-A HERBICIDES FISONS LIMITED (GB) 1979-08-07 US disclosed
US-4156602-A 1-(1-Chloropropyl)-2,4,6-triisopropylbenzene and its use to control weeds PPG INDUSTRIES, INC. (US) 1979-05-29 US disclosed
US-4086081-A PREEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-25 US disclosed
US-4050922-A Substituted benzene-methanol compounds THE DOW CHEMICAL COMPANY (US) 1977-09-27 US disclosed
US-3972913-A Substituted benzenemethanol compounds THE DOW CHEMICAL COMPANY (US) 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12497365-B2 4-pyridinyl formamide compound or derivative thereof, preparation method therefor, herbicidal composition and use thereof CYP4F8, CYP4F11, CYP4F12 MAOA 296/4885MAOB 483/4885DAO 510/4885
US-12509452-B2 Substituted-isoxazoline-containing aromatic compound, preparation method therefor, herbicidal composition and use thereof CYP4X1, CBR3, CYP4B1 MAOA 1072/4885MAOB 1300/4885DAO 118/4885
US-12616203-B2 Use of 3-isoxazolidinones compounds as selective herbicides CNPY2, CRY2, DDT MAOA 729/4885MAOB 2296/4885DAO 684/4885
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD MAOA 539/4885MAOB 998/4885DAO 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.