Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11239731 | 0.81 | HTR6 (0.46) | MAPTMEN1KMT2ATDP1TTR | |
| SCHEMBL11075975 | 0.81 | HCAR3 (0.44) | HCAR3MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL11074643 | 0.81 | MAPT (0.53) | HCAR3MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL11071374 | 0.77 | MEN1 (0.56) | MAPTMEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL10977063 | 0.77 | TDP1 (0.56) | MAPTMEN1KMT2ATDP1TTR | |
| SCHEMBL11246516 | 0.75 | MAPT (0.48) | MAPTMEN1KMT2ATDP1TTR | |
| SCHEMBL11100238 | 0.73 | MEN1 (0.59) | MAPTMEN1KMT2ATDP1TTR | |
| SCHEMBL11098406 | 0.73 | KMT2A (0.44) | HCAR3MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL10975930 | 0.72 | MEN1 (0.57) | MAPTMEN1KMT2ATDP1TTR | |
| SCHEMBL11079813 | 0.72 | MEN1 (0.51) | MAPTMEN1KMT2AL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364875-A | AMINATION, ISOMER-FREE END-PRODUCTS | CELAMERCK GMBH & CO. KG (DE) | 1982-12-21 | — | — | US | disclosed |
| EP-0027555-A1 | Process for the preparation of diphenyl ethers | CELAMERCK GmbH & Co. KG (DE) | 1981-04-29 | — | — | EP | disclosed |