Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400130 | 0.83 | MAPT (0.50) | MAPTKMT2AL3MBTL1HCAR3SIRT5 | |
| SCHEMBL7129606 | 0.83 | MAPT (0.56) | MAPTKMT2AMEN1L3MBTL1HCAR3 | |
| SCHEMBL11225980 | 0.81 | HCAR3 (0.49) | MAPTKMT2AMEN1L3MBTL1HCAR3 | |
| SCHEMBL9725552 | 0.80 | ALDH1A1 (0.52) | MAPTKMT2AMEN1SIRT5RAB9A | |
| SCHEMBL8463547 | 0.78 | TDP1 (0.50) | MAPTKMT2AMEN1L3MBTL1SIRT5 | |
| SCHEMBL1344661 | 0.77 | HCAR3 (0.58) | MAPTKMT2AMEN1L3MBTL1HCAR3 | |
| SCHEMBL566190 | 0.77 | GAA (0.48) | KMT2AMEN1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL12210038 | 0.77 | MAPT (0.53) | MAPTKMT2AL3MBTL1SIRT5RAB9A | |
| SCHEMBL5405448 | 0.75 | MAPT (0.60) | MAPTKMT2AMEN1L3MBTL1HCAR3 | |
| SCHEMBL22191673 | 0.75 | MAPT (0.60) | MAPTKMT2AMEN1L3MBTL1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027555-B1 | PROCESS FOR THE PREPARATION OF DIPHENYL ETHERS | CELAMERCK GmbH & Co. KG (DE) | 1984-01-04 | — | — | EP | disclosed |
| US-4364875-A | AMINATION, ISOMER-FREE END-PRODUCTS | CELAMERCK GMBH & CO. KG (DE) | 1982-12-21 | — | — | US | disclosed |
| EP-0027555-A1 | Process for the preparation of diphenyl ethers | CELAMERCK GmbH & Co. KG (DE) | 1981-04-29 | — | — | EP | disclosed |