SCHEMBL1122608

SCHEMBL1122608

CCCCc1ccc(COc2ccc(C(=O)N(CCC(=O)O)Cc3cccc(OCc4ccccc4)c3)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.59
BCHE P06276 4/20 0.55
FFAR4 Q5NUL3 2/20 0.52
ALOX5 P09917 1/20 0.51
PTGES O14684 1/20 0.51
SMPD1 P17405 1/20 0.50
PPARG P37231 1/20 0.50
SLC2A1 P11166 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122938 0.94 BCHE (0.55) FFAR1BCHEPTGESSMPD1PPARG
SCHEMBL1123389 0.93 BCHE (0.57) FFAR1BCHEFFAR4ALOX5
SCHEMBL1122854 0.91 FFAR1 (0.60) FFAR1FFAR4ALOX5PTGESSMPD1
SCHEMBL1123087 0.90 FFAR1 (0.56) FFAR1BCHEALOX5PTGESSMPD1
SCHEMBL1123113 0.90 FFAR1 (0.62) FFAR1FFAR4ALOX5PTGESSLC2A1
SCHEMBL1122963 0.89 FFAR1 (0.65) FFAR1FFAR4ALOX5PTGESSLC2A1
SCHEMBL1123126 0.89 BCHE (0.53) FFAR1BCHEPTGESSMPD1PPARG
SCHEMBL1123374 0.88 BCHE (0.54) BCHEALOX5
SCHEMBL1123260 0.88 FFAR1 (0.60) FFAR1FFAR4ALOX5PTGESSMPD1
SCHEMBL1123043 0.87 BCHE (0.52) FFAR1BCHEALOX5PTGESSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1644321-B1 NEW BENZAMIDES AS PPATY MODULATORS S A L V A T LAB SA (ES) 2011-02-09 EP claimed
CN-1835914-A New benzamides as PPAR[upsilon] modulators S A L V A T LAB SA (ES) 2006-09-20 CN claimed
US-20060160894-A1 Benzamides as ppar modulators LABORATORIOS S.A.L.V.A.T.,S.A. (ES) 2006-07-20 US claimed
EP-1644321-B1 NEW BENZAMIDES AS PPATY MODULATORS S A L V A T LAB SA (ES) 2011-02-09 EP disclosed
CN-1835914-A New benzamides as PPAR[upsilon] modulators S A L V A T LAB SA (ES) 2006-09-20 CN disclosed
US-20060160894-A1 Benzamides as ppar modulators LABORATORIOS S.A.L.V.A.T.,S.A. (ES) 2006-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060160894-A1 Benzamides as ppar modulators PPARD, PPARA, PPARG FFAR1 32/4885BCHE 520/4885FFAR4 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.