SCHEMBL1123087

SCHEMBL1123087

CCCCc1ccc(COc2ccc(C(=O)N(CC(=O)O)Cc3cccc(OCc4ccccc4)c3)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.56
BCHE P06276 4/20 0.54
SLC2A1 P11166 4/20 0.52
SLC2A4 P14672 1/20 0.51
ALOX5 P09917 2/20 0.50
PTGES O14684 2/20 0.50
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
LTC4S Q16873 1/20 0.49
SMPD1 P17405 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1123268 0.93 BCHE (0.56) FFAR1BCHEALOX5MEN1KMT2A
SCHEMBL1123043 0.91 BCHE (0.52) FFAR1BCHESLC2A1SLC2A4ALOX5
SCHEMBL1122608 0.90 FFAR1 (0.59) FFAR1BCHESLC2A1ALOX5PTGES
SCHEMBL1123013 0.89 FFAR1 (0.58) FFAR1SLC2A1SLC2A4ALOX5PTGES
SCHEMBL1123406 0.87 NR4A2 (0.56) FFAR1SLC2A1SLC2A4ALOX5PTGES
SCHEMBL1123059 0.85 SMPD1 (0.54) BCHESLC2A1SLC2A4PTGESKMT2A
SCHEMBL1122938 0.84 BCHE (0.55) FFAR1BCHEPTGESKMT2ASMPD1
SCHEMBL1123118 0.84 KMT2A (0.58) FFAR1SLC2A1SLC2A4PTGESKMT2A
SCHEMBL1123224 0.83 BCHE (0.53) BCHEALOX5MEN1KMT2A
SCHEMBL1123174 0.82 NR4A2 (0.59) FFAR1BCHESLC2A1SLC2A4ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1644321-B1 NEW BENZAMIDES AS PPATY MODULATORS S A L V A T LAB SA (ES) 2011-02-09 EP claimed
US-20060160894-A1 Benzamides as ppar modulators LABORATORIOS S.A.L.V.A.T.,S.A. (ES) 2006-07-20 US claimed
EP-1644321-A2 NEW BENZAMIDES AS PPATY MODULATORS LABORATORIOS S.A.L.V.A.T., S.A. (ES) 2006-04-12 EP claimed
WO-2004110983-A2 NEW BENZAMIDES AS PPARϒ MODULATORS LABORATORIOS S.A.L.V.A.T., S.A. (ES) 2004-12-23 WO claimed
EP-1644321-B1 NEW BENZAMIDES AS PPATY MODULATORS S A L V A T LAB SA (ES) 2011-02-09 EP disclosed
US-20060160894-A1 Benzamides as ppar modulators LABORATORIOS S.A.L.V.A.T.,S.A. (ES) 2006-07-20 US disclosed
EP-1644321-A2 NEW BENZAMIDES AS PPATY MODULATORS LABORATORIOS S.A.L.V.A.T., S.A. (ES) 2006-04-12 EP disclosed
WO-2004110983-A2 NEW BENZAMIDES AS PPARϒ MODULATORS LABORATORIOS S.A.L.V.A.T., S.A. (ES) 2004-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060160894-A1 Benzamides as ppar modulators PPARD, PPARA, PPARG FFAR1 32/4885BCHE 520/4885SLC2A1 2494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.