Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.55 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 3/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.51 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123113 | 0.97 | FFAR1 (0.62) | FFAR1FFAR4SLC2A1SLC2A4PTGES | |
| SCHEMBL1123559 | 0.96 | FFAR1 (0.62) | FFAR1FFAR4SLC2A1SLC2A4PTGES | |
| SCHEMBL1122854 | 0.95 | FFAR1 (0.60) | FFAR1FFAR4SLC2A1SLC2A4PTGES | |
| SCHEMBL1123260 | 0.92 | FFAR1 (0.60) | FFAR1FFAR4SLC2A1SLC2A4PTGES | |
| SCHEMBL1122984 | 0.90 | NR4A2 (0.56) | FFAR1SLC2A1SLC2A4PTGESALOX5 | |
| SCHEMBL1122949 | 0.90 | FFAR1 (0.52) | FFAR1SLC2A1SLC2A4PTGESALOX5 | |
| SCHEMBL1122608 | 0.89 | FFAR1 (0.59) | FFAR1FFAR4SLC2A1PTGESALOX5 | |
| SCHEMBL1123188 | 0.87 | SLC2A1 (0.52) | FFAR1SLC2A1SLC2A4PTGESSMN1; SMN2 | |
| SCHEMBL1123394 | 0.87 | KMT2A (0.52) | FFAR1FFAR4PTGESTSHRKMT2A | |
| SCHEMBL1123468 | 0.85 | KMT2A (0.54) | FFAR1SLC2A1SLC2A4PTGESTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |