Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123126 | 0.94 | BCHE (0.53) | BCHEPPARGSMPD1FFAR1KMT2A | |
| SCHEMBL1122608 | 0.94 | FFAR1 (0.59) | BCHEPPARGSMPD1FFAR1KMT2A | |
| SCHEMBL1123260 | 0.90 | FFAR1 (0.60) | PPARGSMPD1FFAR1KMT2APTGES | |
| SCHEMBL1122984 | 0.90 | NR4A2 (0.56) | PPARGSMPD1FFAR1KMT2APTGES | |
| SCHEMBL1123059 | 0.87 | SMPD1 (0.54) | BCHEPPARGSMPD1KMT2APTGES | |
| SCHEMBL1123559 | 0.87 | FFAR1 (0.62) | PPARGSMPD1FFAR1KMT2APTGES | |
| SCHEMBL1123389 | 0.87 | BCHE (0.57) | BCHEFFAR1LPAR1 | |
| SCHEMBL1123468 | 0.85 | KMT2A (0.54) | SMPD1FFAR1KMT2APTGESLPAR1 | |
| SCHEMBL1122854 | 0.84 | FFAR1 (0.60) | SMPD1FFAR1PTGESNR4A2 | |
| SCHEMBL1123087 | 0.84 | FFAR1 (0.56) | BCHESMPD1FFAR1KMT2APTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |