SCHEMBL138155

SCHEMBL138155

CCOc1ccc2nc3cc(N)ccc3c(N)c2c1OC(=O)C(C)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
KDM4E B2RXH2 2/20 0.58
HSD17B10 Q99714 2/20 0.58
ALDH1A1 P00352 2/20 0.58
HPGD P15428 2/20 0.58
MAPK1 P28482 1/20 0.58
CASP1 P29466 1/20 0.58
CASP7 P55210 1/20 0.58
TERT O14746 1/20 0.47
ABCB11 O95342 1/20 0.47
LMNA P02545 1/20 0.47
THRB P10828 1/20 0.47
BLM P54132 1/20 0.47
ELANE P08246 1/20 0.40
TNF P01375 2/20 0.34
GAA P10253 1/20 0.34
PDPK1 O15530 1/20 0.34
DHFR P00374 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL6900162 0.99 MAPT (0.57) MAPTMEN1KMT2AKDM4EHSD17B10
SCHEMBL11431835 0.86 MEN1 (0.53) MAPTMEN1KMT2AKDM4EHSD17B10
SCHEMBL11226201 0.81 HSD17B10 (0.49) MAPTMEN1KMT2AKDM4EHSD17B10
Sulfuric Acid SCHEMBL11263163 0.80 MEN1 (0.58) MAPTMEN1KMT2AKDM4EHSD17B10
Lactic Acid SCHEMBL11262321 0.79 KDM4E (0.66) MAPTMEN1KMT2AKDM4EHSD17B10
SCHEMBL1228387 0.78 MEN1 (0.58) MAPTMEN1KMT2AKDM4EHSD17B10
SCHEMBL8355586 0.76 KDM4E (0.43) MAPTMEN1KMT2AKDM4EHSD17B10
SCHEMBL11608363 0.76 MEN1 (0.63) MAPTMEN1KMT2AKDM4EHSD17B10
SCHEMBL11147039 0.76 MEN1 (0.57) MAPTMEN1KMT2AKDM4EHSD17B10
Ethacridine SCHEMBL30006678 0.73 MEN1 (1.00) MAPTMEN1KMT2AKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106458847-B Novel diamine synthesis and liquid crystal aligning agent using the same 东进世美肯株式会社 2020-04-24 CN claimed
EP-3348634-A1 METHOD FOR SEPARATING NUCLEIC ACID FROM SAMPLE COMPRISING NUCLEIC ACID, AND DEVICE THEREFOR Kaneka Corporation (JP) 2018-07-18 EP claimed
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INST SCI & TECH (KR) 2018-03-08 US claimed
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-07-07 US claimed
EP-2940015-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT Korea Advanced Institute of Science and Technology (KR) 2015-11-04 EP claimed
CN-102257379-A A method and apparatus for analysis of a particle CHEMOMETEC AS 2011-11-23 CN claimed
EP-2350617-A2 A METHOD AND APPARATUS FOR ANALYSIS OF A PARTICLE ChemoMetec A/S (DK) 2011-08-03 EP claimed
WO-2010045949-A2 A METHOD AND APPARATUS FOR ANALYSIS OF A PARTICLE CHEMOMETEC A/S (DK) 2010-04-29 WO claimed
EP-0252278-B1 Disinfecting agents and their use in disinfecting the skin and mucous membranes HENKEL KGAA (DE) 1998-08-19 EP claimed
EP-0418647-B1 Method for purifying plasminogen activator inhibitor (PAI-2) BEHRINGWERKE AG (DE) 1994-12-14 EP claimed
US-5204256-A Preincubating a solution with a disulfide-cleaving agent; mixing with an acridine or quinoline to precipitate impurities BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1993-04-20 US claimed
US-4900721-A Disinfectants and their use for disinfecting the skin and mucous membrane HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-02-13 US claimed
US-4104125-A Process for producing human lysozyme THE GREEN CROSS CORPORATION (JP) 1978-08-01 US claimed
US-4017470-A Method for preparing a heat-stable plasma protein solution from paste IV-1 THE GREEN CROSS CORPORATION (JA) 1977-04-12 US claimed
US-3972858-A SILICIC ACID, ELUTION BEHRINGWERKE AKTIENGESELLSCHAFT 1976-08-03 US claimed
JP-3093798-A None JP disclosed
CN-117487569-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2024-02-02 CN disclosed
US-4017470-A Method for preparing a heat-stable plasma protein solution from paste IV-1 THE GREEN CROSS CORPORATION (JA) 1977-04-12 US disclosed
US-3984539-A Bovine immunoglobulin isolation process WAITAKI CANADA LIMITED, C/O OSLER, HOSKIN & HARCOURT, P.O. BOX 50, FIRST CANADIAN PLACE, TORONTO, ONTARIO, CANADA, M5X 1B8, A CANADIAN CORP. 1976-10-05 US disclosed
US-3972858-A SILICIC ACID, ELUTION BEHRINGWERKE AKTIENGESELLSCHAFT 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT RICTOR, SGTA, SLC43A1 MAPT 524/4885MEN1 3853/4885KMT2A 214/4885
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT SGTA, RICTOR, SLC43A1 MAPT 394/4885MEN1 3959/4885KMT2A 209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.