Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14069125 | 0.87 | LMNA (0.50) | LMNACYP1A2KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL18492347 | 0.84 | LMNA (0.70) | LMNACYP1A2KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL12573379 | 0.84 | KDM4E (0.57) | LMNACYP1A2KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL9655894 | 0.84 | CYP1A2 (0.51) | LMNACYP1A2KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL17036958 | 0.83 | LMNA (0.50) | LMNACYP1A2KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL21023425 | 0.83 | LMNA (0.50) | LMNACYP1A2KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL3422910 | 0.82 | ADRB2 (0.51) | LMNACYP1A2KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL11392678 | 0.82 | ALDH1A1 (0.61) | LMNACYP1A2KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL18492332 | 0.82 | CYP1A2 (0.59) | LMNACYP1A2KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL15463392 | 0.81 | ABCB1 (0.60) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4354008-A | CHELATING COMONOMER AND CHELATABLE TRANSITION METAL SALT | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1982-10-12 | — | — | US | claimed |
| US-4354008-A | CHELATING COMONOMER AND CHELATABLE TRANSITION METAL SALT | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1982-10-12 | — | — | US | disclosed |