Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.56 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9893178 | 0.84 | TMIGD3 (0.61) | ADORA1TMIGD3RORCRAB9AADORA2A | |
| SCHEMBL11220024 | 0.80 | ALDH1A1 (0.60) | ADORA1TMIGD3RORCRAB9AALDH1A1 | |
| SCHEMBL9891514 | 0.80 | ADORA1 (0.86) | ADORA1TMIGD3RORCRAB9AADORA2A | |
| SCHEMBL9891912 | 0.80 | ADORA1 (0.57) | ADORA1TMIGD3RORCRAB9AADORA2A | |
| SCHEMBL9892783 | 0.80 | RORC (0.65) | ADORA1TMIGD3RORCRAB9AADORA2A | |
| SCHEMBL4969168 | 0.80 | ADORA1 (0.68) | ADORA1TMIGD3RORCRAB9AADORA2A | |
| SCHEMBL9892839 | 0.79 | ADORA1 (0.52) | ADORA1TMIGD3RORCRAB9AADORA2A | |
| SCHEMBL16253074 | 0.77 | ADORA1 (0.50) | ADORA1TMIGD3RORCRAB9AADORA2A | |
| SCHEMBL13257151 | 0.77 | ADORA1 (0.50) | ADORA1TMIGD3RORCRAB9AADORA2A | |
| SCHEMBL26884163 | 0.76 | RAB9A (0.55) | ADORA1TMIGD3RORCRAB9AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321372-A | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides | PFIZER INC. (US) | 1982-03-23 | — | — | US | disclosed |