Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27925029 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1GAAKMT2ATSHR | |
| SCHEMBL10632634 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1GAAKMT2ATSHR | |
| SCHEMBL27924998 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1GAAKMT2ATSHR | |
| SCHEMBL27792007 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1GAAKMT2ATSHR | |
| SCHEMBL10984015 | 0.79 | GAA (0.45) | SMN1; SMN2MEN1GAAKMT2ATSHR | |
| SCHEMBL16999005 | 0.78 | TSHR (0.62) | SMN1; SMN2MEN1GAAKMT2ATSHR | |
| SCHEMBL11713360 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1GAAKMT2ATSHR | |
| SCHEMBL10955259 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1GAAKMT2ATSHR | |
| SCHEMBL10638947 | 0.76 | CHRM2 (0.44) | SMN1; SMN2MEN1GAAKMT2ATSHR | |
| SCHEMBL9174859 | 0.76 | FDPS (0.49) | SMN1; SMN2MEN1GAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356177-A | Myocardium-protecting pyridine derivatives having an anti-arrhythmic activity and an activity as blood-platelets antiaggregants | C.M. INDUSTRIES (FR) | 1982-10-26 | — | — | US | disclosed |