SCHEMBL1122678

SCHEMBL1122678

C=Cc1cc(Cl)c(Cl)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.45
HPGD P15428 5/20 0.41
HSD17B10 Q99714 5/20 0.41
CYP3A4 P08684 3/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
AHR P35869 6/20 0.36
TSHR P16473 5/20 0.35
CASP1 P29466 1/20 0.35
CYP1B1 Q16678 1/20 0.35
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
HTR3A P46098 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25852175 0.83 CYP3A4 (0.36) ALDH1A1CYP3A4TP53TDP1
SCHEMBL10738398 0.78 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRTP53TDP1
SCHEMBL15107889 0.78 TP53 (0.39) ALDH1A1TSHRTP53TDP1
SCHEMBL4599239 0.78 HSD17B10 (0.50) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL16956527 0.74 ALDH1A1 (0.38) ALDH1A1TSHRTP53TDP1
SCHEMBL15128427 0.74 ALDH1A1 (0.33) ALDH1A1HPGDHSD17B10CYP3A4CRHBP
SCHEMBL12985704 0.74 ALDH1A1 (0.33) ALDH1A1AHRTP53TDP1
SCHEMBL217938 0.73 ALDH1A1 (0.57) ALDH1A1TSHRTP53TDP1
SCHEMBL16313428 0.73 ALDH1A1 (0.34) ALDH1A1HPGDHSD17B10CYP3A4CRHBP
SCHEMBL1259073 0.73 TSHR (0.50) ALDH1A1CYP3A4AHRTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041610-B Polymer enzyme activator and preparation method thereof 苏州麦斯达尔医疗科技有限公司 2024-04-16 CN claimed
CN-116041610-A Polymer enzyme activator and preparation method thereof 苏州麦斯达尔医疗科技有限公司 2023-05-02 CN claimed
US-7718235-B2 Overcoat composition for image recording materials EASTMAN KODAK COMPANY (US) 2010-05-18 US claimed
US-20070141278-A1 OVERCOAT COMPOSITION FOR IMAGE RECORDING MATERIALS BANK OF AMERICA, N.A., AS AGENT 2007-06-21 US claimed
US-7219989-B2 Overcoat composition for image recording materials EASTMAN KODAK COMPANY (US) 2007-05-22 US claimed
US-20040202838-A1 Overcoat composition for image recording materials EASTMAN KODAK COMPANY 2004-10-14 US claimed
CN-116041610-B Polymer enzyme activator and preparation method thereof 苏州麦斯达尔医疗科技有限公司 2024-04-16 CN disclosed
CN-116041610-A Polymer enzyme activator and preparation method thereof 苏州麦斯达尔医疗科技有限公司 2023-05-02 CN disclosed
EP-3283459-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed
US-8802341-B2 Carbon based black toners prepared via limited coalescence process EASTMAN KODAK COMPANY (US) 2014-08-12 US disclosed
US-20130337375-A1 CARBON BASED BLACK TONERS PREPARED VIA LIMITED COALESCENCE PROCESS BANK OF AMERICA, N.A., AS AGENT 2013-12-19 US disclosed
US-6096735-A Benzoheterocyclic derivatives OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 2000-08-01 US disclosed
EP-0765314-A1 BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-04-02 EP disclosed
WO-1995034540-A1 BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-12-21 WO disclosed
US-5149743-A Contacting halostyrene monomer with inifer THE UNIVERSITY OF AKRON (US) 1992-09-22 US disclosed
EP-0468041-A4 HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF 1992-07-22 EP disclosed
EP-0468041-A1 HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF The University of Akron (US) 1992-01-29 EP disclosed
WO-1991012281-A1 HALOGEN TERMINATED POLY(HALOSTYRENES) AND A PROCESS FOR THE PREPARATION THEREOF THE UNIVERSITY OF AKRON (US) 1991-08-22 WO disclosed