Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRG | P23470 | 5/20 | 0.61 |
| ▸ | PTPRC | P08575 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507471 | 0.77 | POLB (0.61) | PTPRGPTPRCMAPTL3MBTL1MEN1 | |
| SCHEMBL11380082 | 0.77 | PTPRG (0.58) | PTPRGPTPRCMAPTL3MBTL1CYP1A2 | |
| SCHEMBL11478443 | 0.76 | HTR1A (0.50) | PTPRGSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL11702592 | 0.75 | PTPRG (0.47) | PTPRGPTPRCMAPTSLC6A2SLC6A4 | |
| SCHEMBL11222844 | 0.75 | CYP11B1 (0.48) | PTPRGMAPTCYP1A2CYP2D6OPRK1 | |
| Hydrochloric Acid SCHEMBL11249222 | 0.74 | PTPRG (0.46) | PTPRGPTPRCMAPTSLC6A2SLC6A4 | |
| SCHEMBL11705494 | 0.72 | CYP1A2 (0.56) | MAPTCYP1A2KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL11227346 | 0.72 | POLB (0.59) | PTPRGPTPRCMAPTCYP1A2CYP2D6 | |
| SCHEMBL9232779 | 0.72 | PTPRG (0.76) | PTPRGPTPRCMAPTL3MBTL1MEN1 | |
| SCHEMBL23709607 | 0.71 | RHEB (0.53) | PTPRGPTPRCMAPTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065974-A1 | ANTIDANDRUFF AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-12-08 | — | — | EP | disclosed |
| WO-1982001819-A1 | ANTIDANDRUFF AGENT | STREHLKE PETER | 1982-06-10 | — | — | WO | disclosed |