Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRG | P23470 | 9/20 | 0.76 |
| ▸ | PTPRC | P08575 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200062 | 0.81 | CES2 (0.51) | PTPRGPTPRCHTTKMT2AL3MBTL1 | |
| SCHEMBL11227010 | 0.72 | PTPRG (0.61) | PTPRGPTPRCMAPTPTPN1KMT2A | |
| SCHEMBL11380082 | 0.70 | PTPRG (0.58) | PTPRGPTPRCMAPTPTGDR2KMT2A | |
| SCHEMBL13802463 | 0.70 | PTPRG (0.70) | PTPRGPTPRCARMRGPRX4PTGDR2 | |
| SCHEMBL16390244 | 0.69 | POLB (0.63) | RAB9A | |
| SCHEMBL2387804 | 0.69 | CES2 (0.58) | TDP1RAB9A | |
| SCHEMBL28814684 | 0.69 | CES2 (0.63) | RAB9A | |
| SCHEMBL9716018 | 0.68 | PTPRG (0.68) | PTPRGPTPRCGAAKMT2AL3MBTL1 | |
| SCHEMBL2225523 | 0.68 | CES2 (0.78) | GAAL3MBTL1RAB9A | |
| SCHEMBL29468149 | 0.68 | CES2 (0.78) | GAAL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040645-A1 | 2-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-12-19 | — | — | WO | claimed |